1. A TALE assembly-based mitochondrial DNA editing system, characterized in that the editing system comprises an RVD library, a mitochondrial localization framework vector, a nuclear localization framework vector, the RVD library comprising at least 192 RVD modules comprising: 160 dual RVD modules, 16 single RVD modules and 16 semi-RVD modules.

2. The mitochondrial DNA editing system of claim 1, wherein: the double RVD module recognizes 2 consecutive DNA bases, from position 1 to 10, in a total of 10 positional sequences, with 16 combinations at each position, thus there are 160 double RVD modules in total; a single RVD module recognizes 1 DNA base, from positions 7-10, there are a total of 4 positional sequences, with 4 possibilities at each position, thus there are 16 single RVD modules in total; the semi-RVD module recognizes 1 DNA base, positions 8-11, and there are 4 positions in sequence, 4 possibilities at each position, and thus there are 16 semi-RVD modules in total.

3. The mitochondrial DNA editing system of claim 2, wherein: double, single and semi RVD vector sequences of different positions in the RVD library generate a sticky end sequence with position specificity after Bsa I restriction enzyme cutting, so that the RVD sequences can be automatically arranged and assembled according to the position sequence, and the TALE with 14-21 bases can be assembled and recognized.

4. The mitochondrial DNA editing system of claim 3, wherein: the amino acid sequence of 160 twin RVDs is as shown in Seq ID NO: 1-160; amino acid sequences of 16 single RVDs such as Seq ID NO: 161-176; amino acid sequence of 16 hemi RVD such as Seq ID NO: 177-192; nucleotide sequences of 160 double RVDs such as Seq ID NO: 203-362; nucleotide sequences of 16 single RVDs such as Seq ID NO: 363-378; nucleotide sequences of 16 hemi RVD such as Seq ID NO: 379 and 394.

5. The mitochondrial DNA editing system of claim 1, wherein the main elements of the mitochondrial localization backbone vector are mitochondrial localization signal (MTS), ccd, in order from 5' to 3 `Toxin b Gene, half Ddda_toxUracil Glycosylase Inhibitor (UGI), ampicillin resistance element; 4 mitochondrial localization framework vectors with nucleotide sequences as set forth in Seq ID NO: 193-196.

6. The mitochondrial DNA editing system of claim 1, wherein the major elements of the nuclear localization backbone are, in order from 5 'to 3', a Nuclear Localization Signal (NLS), a ccdb toxin gene, a half ddatox, a uracil glycosylase inhibitor gene (UGI), a ampicillin resistance element; 4 nuclear localization frameworks the nucleotide sequences of which are shown in Seq ID NO: 197-200.

7. The mitochondrial DNA editing system of claims 5 and 6, wherein: two sides of a toxin gene ccdb of the 4 mitochondria positioning framework vectors and the 4 nucleus positioning framework vectors contain two Bsa I enzyme cutting sites, and different viscous terminals are generated after enzyme cutting and are used for specifically connecting the double RVD module at the No. 1 position and the semi RVD module at the No. 8-11 position.

8. An editing method using the TALE assembly-based mitochondrial DNA editing system according to claim 1, comprising the steps of:

step 1, designing a TALE sequence according to a DNA sequence of a site to be edited, selecting the RVD module and a skeleton vector as claimed in claim 1, completing vector assembly by one step through a Golden Gate cloning method, and forming a cytosine base editor (DdCBE); after the assembled DdCBE vector is subjected to the steps of DH5 alpha conversion competence, monoclonal PCR verification, Sanger sequencing and the like, a correctly assembled DdCBE vector can be obtained;

step 2, transfecting correctly assembled MTS-DdCBE into cells of a species to be edited, or transfecting NLS-DdCBE and a T vector containing an editing site into HEK293FT cells together, detecting the editing efficiency of the DdCBE through Sanger sequencing or high-throughput sequencing, and screening the DdCBE combination with the best editing effect on mitochondrial DNA or the T vector;

step 3, carrying out in-vitro transcription on the DdCBE with the best editing effect, injecting fertilized eggs at the 1-cell stage, and then transplanting embryos to oviducts of receptor animals or obtaining F0 generation animals through in-vitro development; detecting the editing efficiency of F0 generation by Sanger sequencing and high-throughput sequencing, and screening F0 generation animals with high editing efficiency;

and 4, mating the female F0 generation animals with high editing efficiency with wild male animals, and detecting the editing efficiency of the obtained F1 generation animals through Sanger sequencing and high-throughput sequencing, wherein the animals with high editing efficiency have the possibility of simulating human diseases.

9. Use of the editing method of claim 8 for the preparation of an animal model of mitochondrial DNA mutations mimicking human disease.

Background

Transcription activator-like effectors (TALEs) are the core modules of second-generation gene editing tools, which are mainly composed of several 34-amino acid repeat units and specifically recognize DNA sequences using two repeat-variable di-Residues (RVDs) composed of amino acids at positions 12 and 13. Various methods have been reported for assembling TALE modules, but most of these methods are tedious, time-consuming, laborious and costly, and how to efficiently assemble customized TALEs becomes a difficulty in their popularization and application.

Mitochondrial diseases are a major class of diseases characterized by mitochondrial dysfunction. Mitochondrial diseases are often caused by mutations in nuclear genes and mitochondrial DNA, and mitochondrial DNA mutations often cause more serious human diseases, such as mitochondrial encephalomyopathy, ataxia, and the like. The method can realize the cutting of the mutant mitochondrial DNA by adopting ZFN and TALEN plus a mitochondrial positioning signal (MTS), so that the mitochondrial DNA with double-strand break is degraded, but the method cannot be used for constructing a mitochondrial DNA mutation animal model and repairing the mitochondrial DNA mutation and has great limitation. This technique is not useful for mitochondrial DNA editing due to the inability of the sgRNA of CRISPR/Cas9 to enter the mitochondria. Currently, the dddA domain of bacterial toxin proteins, DddA_toxHas double-stranded DNA deaminase activity, and can realize site-directed C/G to T/A mutation in mitochondria by connecting with TALE to form a cytosine base editor (DdCBE). Therefore, a TALE assembly-based mitochondrial DNA editing system is formed by constructing the RVD library and a mitochondrial DNA editing tool vector.

Disclosure of Invention

The invention aims to provide a mitochondrial DNA editing system based on TALE assembly aiming at the problems in the prior art.

Another object of the present invention is to provide an editing method using the mitochondrial DNA editing system.

It is still another object of the present invention to provide the use of the editing method in the preparation of an animal model of mitochondrial DNA mutations that mimics human disease.

The purpose of the invention is realized by the following technical scheme:

a TALE assembly-based mitochondrial DNA editing system comprising an RVD library, a mitochondrial localization framework vector, a nuclear localization framework vector, the RVD library comprising at least 192 RVD modules comprising: 160 dual RVD modules, 16 single RVD modules and 16 semi-RVD modules.

The double RVD module recognizes 2 DNA bases, and has a total of 10 position sequences from the position 1 to 10, and can sequentially correspond to the nucleotides at the positions 1-20 from the 5 'end to the 3' end of the recognized DNA, and each position has 16 combinations, so that the total number of 160 double RVD modules is 160; a single RVD module recognizes 1 DNA base, from positions 7-10, in total 4 positions in order, which may correspond in turn to the nucleotides at positions 13, 15, 17 and 19, from the end of 5 'to the end of 3', with 4 possibilities at each position, thus in total 16 single RVD modules; the semi-RVD module recognizes 1 DNA base, from positions 8-11, and has a total of 4 position sequences, which can correspond to the 14 th, 16 th, 18 th, 20 th and 21 th nucleotides in sequence from the end of DNA5 'to the end of 3', and there are 4 possibilities in each position, so that there are 16 semi-RVD modules in total.

Furthermore, the two ends of the DNA sequence of the RVD modules at different positions contain Bsa I enzyme cutting sites which are used for generating sticky ends of 4 different base sequences so as to determine the connection sequence of the front RVD module and the rear RVD module.

Further, each vector in the RVD library contains a tetracycline resistance element for cloning screening.

The mitochondrial DNA editing system, wherein: double, single and semi RVD vector sequences of different positions in the RVD library generate a sticky end sequence with position specificity after Bsa I restriction enzyme cutting, so that the RVD sequences can be automatically arranged and assembled according to the position sequence, and the TALE with 14-21 bases can be assembled and recognized.

The mitochondrial DNA editing system, wherein: the amino acid sequence of 160 twin RVDs is as shown in Seq ID NO: 1-160; amino acid sequences of 16 single RVDs such as Seq ID NO: 161-176; amino acid sequence of 16 hemi RVD such as Seq ID NO: 177-192; nucleotide sequences of 160 double RVDs such as Seq ID NO: 203-362; nucleotide sequences of 16 single RVDs such as Seq ID NO: 363-378; nucleotide sequences of 16 hemi RVD such as Seq ID NO: 379 and 394.

Note: hereinafter, the bases of the capital letters connected to the 5 'end and the 3' end of the RVD library DNA sequence are Bsa I recognition sites and spacer sequences, and the non-RVD module DNA sequence itself (itself, the bases of the lower case letters).

The mitochondrial DNA editing system, wherein: the main elements of the mitochondrial localization skeleton vector are a mitochondrial localization signal (MTS), a ccdb toxin gene and half Ddda in sequence from the 5 'end to the 3' end_toxUracil Glycosylase Inhibitor (UGI), ampicillin resistance element; 4 mitochondrial localization framework vectors with nucleotide sequences as set forth in Seq ID NO: 193-196.

The mitochondrial DNA editing system is characterized in that the main elements of the cell nucleus positioning skeleton are a cell nucleus positioning signal (NLS), a ccdb toxin gene, a half DddAtox, a Uracil Glycosylase Inhibitor (UGI) and an ampicillin resistant element in sequence from the 5 'end to the 3' end; 4 nuclear localization frameworks the nucleotide sequences of which are shown in Seq ID NO: 197-200.

Further, in Ddda_tox4 half DddA produced by splitting the 1333 amino acid position and the 1397 amino acid position_toxRespectively give half Ddda_toxThe mitochondrial localization signal (MTS) or Nuclear Localization Signal (NLS) was fused, so there were 4 mitochondrial localization backbone vectors and 4 nuclear localization backbone vectors.

Further, Bsa I enzyme cutting sites on each vector contain the ccdb toxin gene, Bsa I enzyme cutting at two ends generates different sticky ends for specifically connecting the double RVD module at the position 1 and the semi RVD module at the position 8-11.

Further, on each vector was placed half Ddda_toxThen contains 1 uracil glycosylase inhibitor gene UGI for improving mitochondria DNA-directed C/G to T/A mutation efficiency.

The editing method of the mitochondrial DNA editing system based on TALE assembly comprises the following steps:

step 1, designing a TALE sequence according to a DNA sequence of a site to be edited, selecting the RVD module and a skeleton vector as claimed in claim 1, completing vector assembly by one step through a Golden Gate cloning method, and forming a cytosine base editor (DdCBE); after the assembled DdCBE vector is subjected to the steps of DH5 alpha conversion competence, monoclonal PCR verification, Sanger sequencing and the like, a correctly assembled DdCBE vector can be obtained;

step 2, transfecting correctly assembled MTS-DdCBE into cells of a species to be edited, or transfecting NLS-DdCBE and a T vector containing an editing site into HEK293FT cells together, detecting the editing efficiency of the DdCBE through Sanger sequencing or high-throughput sequencing, and screening the DdCBE combination with the best editing effect on mitochondrial DNA or the T vector;

step 3, carrying out in-vitro transcription on the DdCBE with the best editing effect, injecting fertilized eggs at the 1-cell stage, and then transplanting embryos to oviducts of receptor animals or obtaining F0 generation animals through in-vitro development; detecting the editing efficiency of F0 generation by Sanger sequencing and high-throughput sequencing, and screening F0 generation animals with high editing efficiency;

and 4, mating the female F0 generation animals with high editing efficiency with wild male animals, and detecting the editing efficiency of the obtained F1 generation animals through Sanger sequencing and high-throughput sequencing, wherein the animals with high editing efficiency have the possibility of simulating human diseases.

The editing method is applied to the preparation of mitochondrial DNA mutation animal models simulating human diseases.

In order to realize the high-efficiency assembly of TALE, the invention constructs the RVD library containing 192 vectors, compared with the RVD library containing 424 vectors reported by Kim Y and the like (Nat Biotechnol.2013Mar; 31(3):251-8.) and the RVD library containing 256 vectors reported by Zhang and the like (PLoS one.2013Jun 20; 8(6): e 66459.). Compared with the STAR method which requires several days (Methods Mol biol.2018; 1772: 477-490), the method only needs 10 rounds of 10-minute enzyme digestion and 10 minutes of connection, and the total 4 hours of reaction can be realizedAnd (6) finishing the assembly. And (3) carrying out colony culture for 12 hours after the transformation of the ligation product, carrying out PCR colony identification and sending to sanger sequencing, and obtaining a correct vector verified by sequencing within 36 hours. In addition, it is against TALE-DddA reported BY Mok BY et al_tox(Nature.2020 Jul; 583(7817): 631. sub. 637.), the mitochondrial DNA editing system based on TALE assembly developed by the invention simplifies the number of the skeleton vectors, can customize and quickly construct the mitochondrial DNA editing vector, and successfully realizes the mitochondrial DNA editing on animals.

The invention can obtain the following beneficial effects:

1) the invention simplifies the RVD module library and obviously improves the TALE assembly efficiency.

2) The TALE assembling method provided by the invention simplifies the flow, is simple to operate and is suitable for popularization and application.

3) The TALE assembly method provided by the invention can obtain a correct vector verified by sequencing within 36 hours.

4) The terminal position of the TALE assembling method provided by the invention is not limited by the T base, and can be any base.

5) According to the invention, a mitochondrion positioning skeleton vector and a nucleus positioning skeleton vector are constructed, for species with a stable cell line, TALE is directly connected to the mitochondrion positioning skeleton vector, then the cell line is transfected, and a high-efficiency DdCBE pair is screened; for species without stable cell lines, highly efficient dcbe pairs can be selected by ligating TALE to the nuclear localization backbone vector and then co-transfecting HEK293FT cells with a T vector containing an editing site. The high-efficiency DdCBE pair can be used for manufacturing a mitochondrial DNA mutation animal model so as to simulate human diseases and can be potentially applied to treatment of the human mitochondrial DNA mutation diseases.

Drawings

FIG. 1 mitochondrial positioning scaffold vector

FIG. 1 DddA with different segmentation types of mitochondrial localization Signal (MTS)_toxThe vector carries ccdb and UGI elements, the ccdb is positioned between two Bsa I enzyme cutting sites, and the vector carries an ampicillin resistance element.

FIG. 2 Nuclear localization backbone vectors.

FIG. 2 DddA with different segmentation types of Nuclear Localization Signal (NLS)_toxThe vector carries ccdb and UGI elements, the ccdb is positioned between two Bsa I enzyme cutting sites, and the vector carries an ampicillin resistance element

Figure 3 schematic of RVD library.

FIG. 3 is a schematic representation of the RVD library vectors with the left hand numbers representing the positions of the RVDs and the dual RVD modules at positions 1-10 for a total of 160 vectors; single RVD modules are located at positions 7-10, for a total of 16 vectors; the semi RVD modules are located at positions 8-11 for a total of 16 vectors. The DNA sequences flanking the RVDs are cohesive terminal DNA sequences resulting from Bsa I cleavage, and each RVD vector is tetracycline resistant.

FIG. 4 conservative analysis of human mitochondrial DNA G3733 mutant pathogenic site.

In FIG. 4, the position indicated by an arrow is an editing site, and gray letters indicate TALE recognition sites, and the gene of the editing site is nd 1. G3733 is the position in human mitochondrial DNA and G4247 is the position in zebrafish mitochondrial DNA.

FIG. 5 conservative analysis of the pathogenic site of human mitochondrial DNA G8363 mutation.

In FIG. 5, the position indicated by an arrow is an editing site, and gray letters indicate TALE recognition sites, and the gene of the editing site is trnk. G8363 is the position in human mitochondrial DNA and G8892 is the position in zebrafish mitochondrial DNA.

FIG. 6 analysis of editing effect of DdCBE on T vector

FIG. 6 left panel shows the efficiency of G4247 editing on T-vector using high throughput sequencing, and FIG. 6 right panel shows the efficiency of G8892 editing on zebrafish mixed embryos using Sanger sequencing, with DdCBE combinations and orientations shown on the X-axis.

FIG. 7F0 generation zebra fish mitochondrial DNA G4247 site editing efficiency analysis.

FIG. 7 left Sanger sequencing was used to analyze the editing effect of DdCBE at the G4247 site, and the editing site is marked by an arrow; FIG. 7 right shows the editing efficiency of DdCBE at the G4247 site in F0 generation zebrafish by high throughput sequencing analysis.

FIG. 8F0 generation zebra fish mitochondrial DNA G8892 site editing efficiency analysis.

FIG. 8 left Sanger sequencing was used to analyze the editing effect of DdCBE at the G8892 site, which is marked by an arrow; FIG. 8 right shows the editing efficiency of DdCBE at the G8892 site in F0 zebrafish by high throughput sequencing analysis.

FIG. 9 Zebra fish body shape and motion trajectory analysis with mitochondrial DNA mutations.

FIG. 9 size analysis of the body types of the left 120-day-old mitochondrial DNA mutant zebra fish and the wild zebra fish; FIG. 9 analysis of the movement traces of the right mitochondrial DNA mutant zebra fish and the wild zebra fish.

FIG. 10 analysis of the motor ability of zebrafish carrying mitochondrial DNA mutations.

FIG. 10 analysis of the movement velocity of mitochondrial DNA mutant zebra fish and wild zebra fish at the age of 120 days; fig. 10 right. And (3) analyzing the movement distance of the 120-day-old mitochondrial DNA mutant zebra fish and the wild zebra fish.

FIG. 11 analysis of the mitochondrial structure of zebrafish carrying mitochondrial DNA mutations.

Mitochondrial DNA mutation of mitochondrial structures in muscle tissues of zebra fish and wild zebra fish are analyzed by a transmission electron microscope.

Detailed Description

The present invention will be described in detail below with reference to examples, whereby it is possible to fully understand how to implement gene editing of mitochondrial DNA by applying the present invention.

The invention is further described below with reference to the accompanying drawings. The invention provides a mitochondrial DNA editing system based on efficient assembly of TALE.

The method for efficiently assembling the TALE is provided, the method needs an RVD library containing 192 vectors and comprises the following steps: 160 dual RVD modules, 16 single RVD modules and 16 semi-RVD modules.

There is also provided, among other things, a mitochondrial DNA editing system that matches an RVD library, the system comprising: 8 vectors.

In this system, assembling the RVD library of TALEs and the mitochondrial DNA editing system matched to the RVD library can be accomplished within 36 hours by reaction in one system. The system is efficient, low in price, simple to operate and easy to popularize, and is an important innovation optimized in long-term research and practice of the subject group.

Example 1

And constructing a zebra fish mitochondrial DNA mutation model by utilizing a mitochondrial DNA editing system based on efficient assembly of TALE, and simulating a human disease model.

Selection of RVD module and assembly of TALE

The pathogenic mutation sites of C/T to G/A of G3733 and G8363 on human mitochondrial DNA (reference sequence version: NC-012920.1) were selected and the corresponding target sites were screened for based on conservation analysis (FIGS. 4 and 5). For these 2 pathogenic mutation sites, the corresponding G4247 and G8892 sites on zebrafish were designed (reference sequence version: NC-002333.2). Based on the DNA sequence, RVDs at corresponding positions are selected in the RVD library of the invention, such as: (ii) the 1 st and 2 nd bases of the DNA sequence are GT, and the RVD module in the RVD library which recognizes the GT sequence at position 1 is selected; when bases 3 and 4 are AG, the RVD module in the RVD library that recognizes the AG sequence at position 2 is selected, and so on. When the length of the DNA sequence is odd, the semi-RVD module corresponding to the last base is selected. And when the sequence length is even, selecting a single RVD module corresponding to the last but one base and selecting a semi RVD module corresponding to the last base.

Here, for example, G4247 is exemplified by an odd-numbered nucleotide sequence G4247A-R15: AATAGAATAAGTCCT selecting RVD modules as 7 double RVDs and 1 half RVD; the RVD combinations are as follows: AA1, TA2, GA3, AT4, AA5, GT6, CC7, and hT 8. Such as an even number of base sequences G4247A-L16: GTAGCGCAAACAATTT selecting RVD modules as 7 double RVDs and 1 single RVD and 1 semi RVD; the RVD combinations are as follows: GT1, AG2, CG3, CA4, AA5, CA6, AT7, pC8 and hT 9.

Mitochondrially-localized backbone vectors or nucleus-localized backbone vectors (FIGS. 1 and 2), with selected RVD modules, where the number of RVD modules is related to the length of DNA sequence recognized by the TALE, were added to the PCR tubes according to the system of Table 1, with the reagent sources given in the table. The reaction was carried out in a PCR instrument using the following reaction conditions: 10 cycles of 10min at 37 ℃ and 10min at 16 ℃; 5min at 50 ℃; 5min at 80 ℃; hold at4 ℃. Due to the existence of Bsa I endonuclease and T4 ligase, the digestion and ligation of the vector can be simultaneously realized in one reaction system.

Table 1: TALE library assembly reaction system

Composition (I)	Volume (μ L)
		RVD module (50 ng/. mu.L)	0.5each
Skeleton carrier (100 ng/. mu.L)	1
		T4 Buffer(NEB)	1
T4 DNAligase(NEB)	0.5
		Bsa I(NEB)	0.5
Adding H2O is supplemented to	10

After the reaction was completed, the product was transformed into DH 5. alpha. and screened using a solid LB plate containing ampicillin, after which a single clone was picked and identified by PCR using the primers shown in Seq ID No. 201-202. Positive clones are judged according to the number of RVDs, for example, 16 RVDs are 1759bp in size, and 15 RVDs are 1657bp in size. Then, the primers are used for positive and negative sequencing, and the positive clone with the correct sequence is used for extracting the plasmid for subsequent experiments.

(II) detection of DdCBE editing efficiency in vitro cells

For the animal zebrafish without an available cell line, the sequences of the editing sites shown in fig. 4 and 5 can be cloned into the T-vector first. When the density of HEK293FT cells reaches 70-90%, changing liquid 2 hours in advance, counting cells, and taking 10⁵Each cell was used for cell electrotransfection (instrument: Lonza 4D-nucleofector). As shown in FIGS. 4 and 5, 400ng and 50ng each of the T vectors containing an editing site of DdCBE recognizing the DNA sequences at the left and right ends were mixed, followed by electrotransfection of HEK293FT cells using SF-Cell Line 4D-nucleofector X-kit. For animals with available cell lines, 400ng each of DdCBE recognizing DNA sequences at both right and left ends can be electroporated directly by the same method as described above.

After completion of the electrotransfection, the cells were plated in 12-well plates and cultured for 24 hours, followed by cell selection using puromycin containing 2. mu.g/mL, digestion and centrifugation of the cells after 48 hours of culture, and harvesting the cells for detection of DNA mutation efficiency.

The DNA of the collected cell sample is extracted in the following way: quickextract using 30. mu.L^TMThe cells were re-selected by DNA Extraction Solution (Lucigen) followed by heating at 65 ℃ for 45min, followed by vortex centrifugation and heating using 98 ℃ for 2 min.

Amplifying target fragments containing editing sites on T-vector or mitochondrial DNA by using 2 XGreen Taq Mix (Vazyme), and then using the target fragments for Sanger sequencing; or carrying out high-throughput sequencing analysis editing efficiency by using Phanta Super-Fidelity DNA polymerase (Vazyme) and a high-throughput sequencing library-establishing primer. The editing effect of high throughput sequencing is shown in figure 6.

(III) construction of mitochondrial DNA mutant zebra fish model by using DdCBE

Based on Sanger sequencing and high throughput sequencing results compiled in vivo, dcbe combinations at G4247 and G8892 sites with the highest compilation efficiency were screened. 10. mu.g each of DdCBE vectors recognizing the DNA sequences on the left and right sides was mixed, and then the vectors were linearized using a Pme I (NEB) restriction enzyme. DNA was recovered using DNA Clean & concentrator TM-5 Kit (Zymo Research), followed by in vitro transcription using mMESSAGE mMACHINE T7 Ultra Kit (Life, AM1345) according to the instructions, and transcribed mRNA was recovered using RNA Clean & concentrator TM-5(Zymo Research) and stored frozen at-80 ℃.

In order to obtain zebra fish with mitochondrial DNA mutation, injection was performed at the 1-cell stage of zebra fish, and the injection concentration of RNA was 100 ng/. mu.L. Collecting the obtained F0-generation zebra fish tissues, extracting DNA, and performing Sanger sequencing and high-throughput sequencing by the method in the step (II), wherein the editing effect of F0-generation zebra fish is high and low, the editing efficiency on G4247 site mutant zebra fish mitochondrial DNA is 6.36-23.48%, and the editing efficiency on G8892 site mutant zebra fish mitochondrial DNA is 5.78-88.32% as shown in FIGS. 7 and 8.

(IV) zebra fish simulated human disease model carrying mitochondrial DNA mutation

Firstly, G4247 and G8892 site mutation female zebra fish with higher editing efficiency are selected to be mated with wild male zebra fish, and F1 generation zebra fish is obtained. As shown in table 2, zebrafish of the F1 generation were obtained with higher or lower editing efficiency than the F0 generation.

Table 2: editing efficiency analysis of F1-generation zebra fish

To verify whether zebrafish carrying mitochondrial mutations can mimic human disease. The zebra fish of the F1 generation with the high editing efficiency of G4247A was selected for phenotypic analysis, and the results shown in FIGS. 9-11 indicate that the zebra fish of the F1 generation is damaged in motor function and the mitochondrial spine structure in muscle tissue is destroyed. Therefore, the zebra fish animal model with mitochondrial DNA mutation generated by editing the mitochondrial DNA editing system based on the efficient assembly of TALE can simulate mitochondrial diseases caused by human mitochondrial DNA mutation.

The above description shows and describes embodiments of the invention, and in summary, the invention provides a mitochondrial DNA editing system based on TALE assembly, including a method for rapidly assembling TALE modules and a mitochondrial DNA editing system matched to TALE assembly. Experiments prove that the TALE assembly-based mitochondrial DNA editing system has the advantages that the TALE module is efficiently assembled and low in price, and the TALE assembly-based mitochondrial DNA editing system is simple to operate and easy to popularize; meanwhile, mitochondrial DNA editing can be successfully realized by utilizing a mitochondrial DNA editing system of a matching and TALE module high-speed assembly method. Besides zebra fish, the method disclosed by the invention has also been successfully used for constructing mitochondrial DNA mutation animal models of mice, rats, monkeys and the like, and the method is proved to have good stability and repeatability.

(I) RVD library amino acid sequences

1)AA1

PEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPD

2)AA2

QVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQV

3)AA3

VAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQV

4)AA4

VAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVV

5)AA5

AIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVA

6)AA6

IASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAI

7)AA7

ASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA

8)AA8

SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA

9)AA9

SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA

10)AA10

SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIAS

11)AC1

PEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPA

12)AC2

QVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQV

13)AC3

VAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQV

14)AC4

VAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVV

15)AC5

AIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVA

16)AC6

IASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAI

17)AC7

ASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA

18)AC8

SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA

19)AC9

SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA

20)AC10

SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIAS

21)AG1

PEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPE

22)AG2

QVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQV

23)AG3

VAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQV

24)AG4

VAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVV

25)AG5

AIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVA

26)AG6

IASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAI

27)AG7

ASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

28)AG8

SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

29)AG9

SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

30)AG10

SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIAS

31)AT1

PEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPE

32)AT2

QVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQV

33)AT3

VAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQV

34)AT4

VAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVV

35)AT5

AIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVA

36)AT6

IASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAI

37)AT7

ASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

38)AT8

SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

39)AT9

SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

40)AT10

SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIAS

41)CA1

PEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPD

42)CA2

QVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQV

43)CA3

VAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQV

44)CA4

VAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVV

45)CA5

AIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVA

46)CA6

IASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAI

47)CA7

ASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA

48)CA8

SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA

49)CA9

SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA

50)CA10

SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIAS

51)CC1

PEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPA

52)CC2

QVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQV

53)CC3

VAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQV

54)CC4

VAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVV

55)CC5

AIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVA

56)CC6

IASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAI

57)CC7

ASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA

58)CC8

SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA

59)CC9

SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA

60)CC10

SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIAS

61)CG1

PEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPE

62)CG2

QVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQV

63)CG3

VAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQV

64)CG4

VAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVV

65)CG5

AIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVA

66)CG6

IASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAI

67)CG7

ASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

68)CG8

SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

69)CG9

SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

70)CG10

SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIAS

71)CT1

PEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPE

72)CT2

QVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQV

73)CT3

VAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQV

74)CT4

VAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVV

75)CT5

AIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVA

76)CT6

IASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAI

77)CT7

ASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

78)CT8

SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

79)CT9

SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

80)CT10

SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIAS

81)GA1

PEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPD

82)GA2

QVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQV

83)GA3

VAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQV

84)GA4

VAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVV

85)GA5

AIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVA

86)GA6

IASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAI

87)GA7

ASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA

88)GA8

SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA

89)GA9

SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA

90)GA10

SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIAS

91)GC1

PEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPA

92)GC2

QVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQV

93)GC3

VAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQV

94)GC4

VAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVV

95)GC5

AIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVA

96)GC6

IASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAI

97)GC7

ASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA

98)GC8

SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA

99)GC9

SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA

100)GC10

SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIAS

101)GG1

PEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPE

102)GG2

QVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQV

103)GG3

VAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQV

104)GG4

VAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVV

105)GG5

AIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVA

106)GG6

IASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAI

107)GG7

ASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

108)GG8

SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

109)GG9

SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

110)GG10

SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIAS

111)GT1

PEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPE

112)GT2

QVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQV

113)GT3

VAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQV

114)GT4

VAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVV

115)GT5

AIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVA

116)GT6

IASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAI

117)GT7

ASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

118)GT8

SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

119)GT9

SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

120)GT10

SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIAS

121)TA1

PEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPD

122)TA2

QVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQV

123)TA3

VAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQV

124)TA4

VAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVV

125)TA5

AIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVA

126)TA6

IASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAI

127)TA7

ASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA

128)TA8

SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA

129)TA9

SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA

130)TA10

SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIAS

131)TC1

PEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPA

132)TC2

QVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQV

133)TC3

VAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQV

134)TC4

VAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVV

135)TC5

AIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVA

136)TC6

IASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAI

137)TC7

ASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA

138)TC8

SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA

139)TC9

SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA

140)TC10

SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIAS

141)TG1

PEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPE

142)TG2

QVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQV

143)TG3

VAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQV

144)TG4

VAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVV

145)TG5

AIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVA

146)TG6

IASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAI

147)TG7

ASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

148)TG8

SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

149)TG9

SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

150)TG10

SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIAS

151)TT1

PEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPE

152)TT2

QVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQV

153)TT3

VAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQV

154)TT4

VAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVV

155)TT5

AIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVA

156)TT6

IASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAI

157)TT7

ASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

158)TT8

SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

159)TT9

SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

160)TT10

SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIAS

161)pA7

ASNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA

162)pA8

SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA

163)pA9

SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIA

164)pA10

SNIGGKQALETVQRLLPVLCQAHGLTPDQVVAIAS

165)pC7

ASHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA

166)pC8

SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA

167)pC9

SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIA

168)pC10

SHDGGKQALETVQRLLPVLCQAHGLTPAQVVAIAS

169)pG7

ASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

170)pG8

SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

171)pG9

SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

172)pG10

SNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIAS

173)pT7

ASNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

174)pT8

SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

175)pT9

SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIA

176)pT10

SNGGGKQALETVQRLLPVLCQAHGLTPEQVVAIAS

177)hA8

SNIGGRPALESIVAQLSRPDPALAA

178)hA9

SNIGGRPALESIVAQLSRPDPALAA

179)hA10

SNIGGRPALESIVAQLSRPDPALAA

180)hA11

GLGQILAAGRRWRALLPSYLALIRRWP

181)hC8

SHDGGRPALESIVAQLSRPDPALAA

182)hC9

SHDGGRPALESIVAQLSRPDPALAA

183)hC10

SHDGGRPALESIVAQLSRPDPALAA

184)hC11

GLGHMTAAGRRWRALLPSYLALIRRWP

185)hG8

SNNGGRPALESIVAQLSRPDPALAA

186)hG9

SNNGGRPALESIVAQLSRPDPALAA

187)hG10

SNNGGRPALESIVAQLSRPDPALAA

188)hG11

GLGQTMAAGRRWRALLPSYLALIRRWP

189)hT8

SNGGGRPALESIVAQLSRPDPALAA

190)hT9

SNGGGRPALESIVAQLSRPDPALAA

191)hT10

SNGGGRPALESIVAQLSRPDPALAA

192)hT11

GLGQMGAAGRRWRALLPSYLALIRRWP

(II) RVD library DNA sequence

1)AA1

GGTCTCGccccggagcaggtggtggccatcgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaggTGAGACC

2)AA2

GGTCTCGcaggttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagtggtTGAGACC

3)AA3

GGTCTCGtggtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagTGAGACC

4)AA4

GGTCTCGgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcaaTGAGACC

5)AA5

GGTCTCGgcaattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattTGAGACC

6)AA6

GGTCTCGgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgatagccTGAGACC

7)AA7

GGTCTCGagccagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcaagtTGAGACC

8)AA8

GGTCTCGaagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcttccTGAGACC

9)AA9

GGTCTCGttccaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcctctTGAGACC

10)AA10

GGTCTCGctctaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcgtcaTGAGACC

11)AC1

GGTCTCGccccggagcaggtggtggccatcgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaggTGAGACC

12)AC2

GGTCTCGcaggttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagtggtTGAGACC

13)AC3

GGTCTCGtggtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagTGAGACC

14)AC4

GGTCTCGgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcaaTGAGACC

15)AC5

GGTCTCGgcaattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattTGAGACC

16)AC6

GGTCTCGgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgatagccTGAGACC

17)AC7

GGTCTCGagccagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcaagtTGAGACC

18)AC8

GGTCTCGaagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcttccTGAGACC

19)AC9

GGTCTCGttccaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcctctTGAGACC

20)AC10

GGTCTCGctctaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcgtcaTGAGACC

21)AG1

GGTCTCGccccggagcaggtggtggccatcgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaggTGAGACC

22)AG2

GGTCTCGcaggttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagtggtTGAGACC

23)AG3

GGTCTCGtggtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagTGAGACC

24)AG4

GGTCTCGgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcaaTGAGACC

25)AG5

GGTCTCGgcaattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattTGAGACC

26)AG6

GGTCTCGgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgatagccTGAGACC

27)AG7

GGTCTCGagccagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcaagtTGAGACC

28)AG8

GGTCTCGaagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcttccTGAGACC

29)AG9

GGTCTCGttccaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcctctTGAGACC

30)AG10

GGTCTCGctctaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcgtcaTGAGACC

31)AT1

GGTCTCGccccggagcaggtggtggccatcgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaggTGAGACC

32)AT2

GGTCTCGcaggttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagtggtTGAGACC

33)AT3

GGTCTCGtggtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagTGAGACC

34)AT4

GGTCTCGgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcaaTGAGACC

35)AT5

GGTCTCGgcaattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattTGAGACC

36)AT6

GGTCTCGgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgatagccTGAGACC

37)AT7

GGTCTCGagccagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcaagtTGAGACC

38)AT8

GGTCTCGaagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcttccTGAGACC

39)AT9

GGTCTCGttccaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcctctTGAGACC

40)AT10

GGTCTCGctctaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcgtcaTGAGACC

41)CA1

GGTCTCGccccggagcaggtggtggccatcgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaggTGAGACC

42)CA2

GGTCTCGcaggttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagtggtTGAGACC

43)CA3

GGTCTCGtggtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagTGAGACC

44)CA4

GGTCTCGgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcaaTGAGACC

45)CA5

GGTCTCGgcaattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattTGAGACC

46)CA6

GGTCTCGgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgatagccTGAGACC

47)CA7

GGTCTCGagccagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcaagtTGAGACC

48)CA8

GGTCTCGaagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcttccTGAGACC

49)CA9

GGTCTCGttcccatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcctctTGAGACC

50)CA10

GGTCTCGctctcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcgtcaTGAGACC

51)CC1

GGTCTCGccccggagcaggtggtggccatcgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaggTGAGACC

52)CC2

GGTCTCGcaggttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagtggtTGAGACC

53)CC3

GGTCTCGtggtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagTGAGACC

54)CC4

GGTCTCGgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcaaTGAGACC

55)CC5

GGTCTCGgcaattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattTGAGACC

56)CC6

GGTCTCGgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgatagccTGAGACC

57)CC7

GGTCTCGagccagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcaagtTGAGACC

58)CC8

GGTCTCGaagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcttccTGAGACC

59)CC9

GGTCTCGttcccatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcctctTGAGACC

60)CC10

GGTCTCGctctcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcgtcaTGAGACC

61)CG1

GGTCTCGccccggagcaggtggtggccatcgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaggTGAGACC

62)CG2

GGTCTCGcaggttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagtggtTGAGACC

63)CG3

GGTCTCGtggtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagTGAGACC

64)CG4

GGTCTCGgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcaaTGAGACC

65)CG5

GGTCTCGgcaattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattTGAGACC

66)CG6

GGTCTCGgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgatagccTGAGACC

67)CG7

GGTCTCGagccagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcaagtTGAGACC

68)CG8

GGTCTCGaagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcttccTGAGACC

69)CG9

GGTCTCGttcccatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcctctTGAGACC

70)CG10

GGTCTCGctctcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcgtcaTGAGACC

71)CT1

GGTCTCGccccggagcaggtggtggccatcgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaggTGAGACC

72)CT2

GGTCTCGcaggttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagtggtTGAGACC

73)CT3

GGTCTCGtggtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagTGAGACC

74)CT4

GGTCTCGgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcaaTGAGACC

75)CT5

GGTCTCGgcaattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattTGAGACC

76)CT6

GGTCTCGgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgatagccTGAGACC

77)CT7

GGTCTCGagccagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcaagtTGAGACC

78)CT8

GGTCTCGaagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcttccTGAGACC

79)CT9

GGTCTCGttcccatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcctctTGAGACC

80)CT10

GGTCTCGctctcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcgtcaTGAGACC

81)GA1

GGTCTCGccccggagcaggtggtggccatcgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaggTGAGACC

82)GA2

GGTCTCGcaggttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagtggtTGAGACC

83)GA3

GGTCTCGtggtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagTGAGACC

84)GA4

GGTCTCGgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcaaTGAGACC

85)GA5

GGTCTCGgcaattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattTGAGACC

86)GA6

GGTCTCGgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgatagccTGAGACC

87)GA7

GGTCTCGagccagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcaagtTGAGACC

88)GA8

GGTCTCGaagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcttccTGAGACC

89)GA9

GGTCTCGttccaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcctctTGAGACC

90)GA10

GGTCTCGctctaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcgtcaTGAGACC

91)GC1

GGTCTCGccccggagcaggtggtggccatcgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaggTGAGACC

92)GC2

GGTCTCGcaggttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagtggtTGAGACC

93)GC3

GGTCTCGtggtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagTGAGACC

94)GC4

GGTCTCGgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcaaTGAGACC

95)GC5

GGTCTCGgcaattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattTGAGACC

96)GC6

GGTCTCGgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgatagccTGAGACC

97)GC7

GGTCTCGagccagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcaagtTGAGACC

98)GC8

GGTCTCGaagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcttccTGAGACC

99)GC9

GGTCTCGttccaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcctctTGAGACC

100)GC10

GGTCTCGctctaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcgtcaTGAGACC

101)GG1

GGTCTCGccccggagcaggtggtggccatcgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaggTGAGACC

102)GG2

GGTCTCGcaggttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagtggtTGAGACC

103)GG3

GGTCTCGtggtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagTGAGACC

104)GG4

GGTCTCGgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcaaTGAGACC

105)GG5

GGTCTCGgcaattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattTGAGACC

106)GG6

GGTCTCGgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgatagccTGAGACC

107)GG7

GGTCTCGagccagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcaagtTGAGACC

108)GG8

GGTCTCGaagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcttccTGAGACC

109)GG9

GGTCTCGttccaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcctctTGAGACC

110)GG10

GGTCTCGctctaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcgtcaTGAGACC

111)GT1

GGTCTCGccccggagcaggtggtggccatcgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaggTGAGACC

112)GT2

GGTCTCGcaggttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagtggtTGAGACC

113)GT3

GGTCTCGtggtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagTGAGACC

114)GT4

GGTCTCGgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcaaTGAGACC

115)GT5

GGTCTCGgcaattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattTGAGACC

116)GT6

GGTCTCGgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgatagccTGAGACC

117)GT7

GGTCTCGagccagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcaagtTGAGACC

118)GT8

GGTCTCGaagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcttccTGAGACC

119)GT9

GGTCTCGttccaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcctctTGAGACC

120)GT10

GGTCTCGctctaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcgtcaTGAGACC

121)TA1

GGTCTCGccccggagcaggtggtggccatcgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaggTGAGACC

122)TA2

GGTCTCGcaggttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagtggtTGAGACC

123)TA3

GGTCTCGtggtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagTGAGACC

124)TA4

GGTCTCGgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcaaTGAGACC

125)TA5

GGTCTCGgcaattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattTGAGACC

126)TA6

GGTCTCGgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgatagccTGAGACC

127)TA7

GGTCTCGagccagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcaagtTGAGACC

128)TA8

GGTCTCGaagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcttccTGAGACC

129)TA9

GGTCTCGttccaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcctctTGAGACC

130)TA10

GGTCTCGctctaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcgtcaTGAGACC

131)TC1

GGTCTCGccccggagcaggtggtggccatcgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaggTGAGACC

132)TC2

GGTCTCGcaggttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagtggtTGAGACC

133)TC3

GGTCTCGtggtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagTGAGACC

134)TC4

GGTCTCGgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcaaTGAGACC

135)TC5

GGTCTCGgcaattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattTGAGACC

136)TC6

GGTCTCGgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgatagccTGAGACC

137)TC7

GGTCTCGagccagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcaagtTGAGACC

138)TC8

GGTCTCGaagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcttccTGAGACC

139)TC9

GGTCTCGttccaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcctctTGAGACC

140)TC10

GGTCTCGctctaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcgtcaTGAGACC

141)TG1

GGTCTCGccccggagcaggtggtggccatcgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaggTGAGACC

142)TG2

GGTCTCGcaggttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagtggtTGAGACC

143)TG3

GGTCTCGtggtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagTGAGACC

144)TG4

GGTCTCGgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcaaTGAGACC

145)TG5

GGTCTCGgcaattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattTGAGACC

146)TG6

GGTCTCGgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgatagccTGAGACC

147)TG7

GGTCTCGagccagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcaagtTGAGACC

148)TG8

GGTCTCGaagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcttccTGAGACC

149)TG9

GGTCTCGttccaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcctctTGAGACC

150)TG10

GGTCTCGctctaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcgtcaTGAGACC

151)TT1

GGTCTCGccccggagcaggtggtggccatcgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaggTGAGACC

152)TT2

GGTCTCGcaggttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagtggtTGAGACC

153)TT3

GGTCTCGtggtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagTGAGACC

154)TT4

GGTCTCGgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcaaTGAGACC

155)TT5

GGTCTCGgcaattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattTGAGACC

156)TT6

GGTCTCGgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgatagccTGAGACC

157)TT7

GGTCTCGagccagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcaagtTGAGACC

158)TT8

GGTCTCGaagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcttccTGAGACC

159)TT9

GGTCTCGttccaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcctctTGAGACC

160)TT10

GGTCTCGctctaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgctagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcgtcaTGAGACC

161)pA7

GGTCTCGagccagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcaagtTGAGACC

162)pA8

GGTCTCGaagtaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcttccTGAGACC

163)pA9

GGTCTCGttccaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcctctTGAGACC

164)pA10

GGTCTCGctctaatattggtggcaaacaggctcttgagacggttcagcgcctccttccagttctctgtcaagcccacggactcaccccagatcaagttgtagcgattgcgtcaTGAGACC

165)pC7

GGTCTCGagccagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcaagtTGAGACC

166)pC8

GGTCTCGaagtcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcttccTGAGACC

167)pC9

GGTCTCGttcccatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcctctTGAGACC

168)pC10

GGTCTCGctctcatgacggtggcaaacaggctcttgaaaccgtccaacgccttctaccagttctctgtcaagcccacggactaaccccagcgcaagttgtagcgattgcgtcaTGAGACC

169)pG7

GGTCTCGagccagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcaagtTGAGACC

170)pG8

GGTCTCGaagtaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcttccTGAGACC

171)pG9

GGTCTCGttccaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcctctTGAGACC

172)pG10

GGTCTCGctctaacaatggtggcaaacaggctcttgaaaccgtacagcgcctactgccagttctctgtcaagcccacggtctgactccggagcaagttgtagcgattgcgtcaTGAGACC

173)pT7

GGTCTCGagccagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcaagtTGAGACC

174)pT8

GGTCTCGaagtaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcttccTGAGACC

175)pT9

GGTCTCGttccaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcctctTGAGACC

176)pT10

GGTCTCGctctaatgggggtggcaaacaggctcttgagactgttcagcgccttctaccagttctctgtcaagcccacggcctgacgcccgagcaagttgtagcgattgcgtcaTGAGACC

177)hA8

GGTCTCGaagtaatattggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC

178)hA9

GGTCTCGttccaatattggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC

179)hA10

GGTCTCGctctaatattggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC

180)hA11

GGTCTCGgtcaaatattggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC

181)hC8

GGTCTCGaagtcatgacggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC

182)hC9

GGTCTCGttcccatgacggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC

183)hC10

GGTCTCGctctcatgacggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC

184)hC11

GGTCTCGgtcacatgacggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC

185)hG8

GGTCTCGaagtaacaatggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC

186)hG9

GGTCTCGttccaacaatggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC

187)hG10

GGTCTCGctctaacaatggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC

188)hG11

GGTCTCGgtcaaacaatggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC

189)hT8

GGTCTCGaagtaatgggggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC

190)hT9

GGTCTCGttccaatgggggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC

191)hT10

GGTCTCGctctaatgggggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC

192)hT11

GGTCTCGgtcaaatgggggcggcaggccggcgctggagagcattgttgcccagttatctcgccctgatccggcgttggccgcgTGAGACC

(III) positioning skeleton DNA sequence

1)MTS-G1333N

atgttggggtttgtgggtcgggtggccgctgctccggcctccggggccttgcggagactcaccccttcagcgtcgctgcccccagctcagctcttactgcgggccgctccgacggcggtccatcctgtcagggactatgcggcgcaaacatctgagagcggcggaggcgggagccccggcgcggccgctgactacaaggatgacgacgataaaggtagcgtggatctacgcacgctcggctacagccagcagcaacaggagaagatcaaaccgaaggttcgttcgacagtggcgcagcaccacgaggcactggtcggccatgggtttacacacgcgcacatcgttgcgctcagccaacacccggcagcgttagggaccgtcgctgtcaagtatcaggacatgatcgcagcgttgccagaggcgacacacgaagcgatcgttggcgtcggcaaacagtggtccggcgcacgcgctctggaggccttgctcacggtggcgggagagttgagaggtccaccgttacagttggacacaggccaacttctcaagattgcaaaacgtggcggcgtgaccgcagtggaggcagtgcatgcatggcgcaatgcactgacgggtgcccccctgaacctgaccccagagaccggcttactaaaagccagataacagtatgcgtatttgcgcgctgatttttgcggtataagaatatatactgatatgtatacccgaagtatgtcaaaaagaggtatgctatgaagcagcgtattacagtgacagttgacagcgacagctatcagttgctcaaggcatatatgatgtcaatatctccggtctggtaagcacaaccatgcagaatgaagcccgtcgtctgcgtgccgaacgctggaaagcggaaaatcaggaagggatggctgaggtcgcccggtttattgaaatgaacggctcttttgctgacgagaacaggggctggtgaaatgcagtttaaggtttacacctataaaagagagagccgttatcgtctgtttgtggatgtacagagtgatattattgacacgcccgggcgacggatggtgatccccctggccagtgcacgtctgctgtcagataaagtctcccgtgaactttacccggtggtgcatatcggggatgaaagctggcgcatgatgaccaccgatatggccagtgtgccggtgtccgttatcggggaagaagtggctgatctcagccaccgcgaaaatgacatcaaaaacgccattaacctgatgttctggggaatataaatgtcaggctcccttatacacagccagggtctctcgcgttgaccaacgaccacctcgtcgccttggcctgcctcggcggacgtcctgcgctggatgcagtgaaaaagggattgggaggctccggctcctacgccctgggcccatatcagatctctgccccacagctgccagcatacaacggacagaccgtgggcacattctactatgtgaatgacgccggcggcctggagtctaaggtgtttagctccggcggctctggaggcagcaccaacctgtctgacatcatcgagaaggagacaggcaagcagctggtcatccaggagagcatcctgatgctgcccgaagaagtcgaagaagtgatcggaaacaagcctgagagcgatatcctggtccataccgcctacgacgagagtaccgacgaaaatgtgatgctgctgacatccgacgccccagagtataagccctgggctctggtcatccaggattccaacggagagaacaaaatcaaaatgctg

2)MTS-G1333C

atgttggggtttgtgggtcgggtggccgctgctccggcctccggggccttgcggagactcaccccttcagcgtcgctgcccccagctcagctcttactgcgggccgctccgacggcggtccatcctgtcagggactatgcggcgcaaacatctgagagcggcggaggcgggagccccggcgcggccgctgactacaaggatgacgacgataaaggtagcgtggatctacgcacgctcggctacagccagcagcaacaggagaagatcaaaccgaaggttcgttcgacagtggcgcagcaccacgaggcactggtcggccatgggtttacacacgcgcacatcgttgcgctcagccaacacccggcagcgttagggaccgtcgctgtcaagtatcaggacatgatcgcagcgttgccagaggcgacacacgaagcgatcgttggcgtcggcaaacagtggtccggcgcacgcgctctggaggccttgctcacggtggcgggagagttgagaggtccaccgttacagttggacacaggccaacttctcaagattgcaaaacgtggcggcgtgaccgcagtggaggcagtgcatgcatggcgcaatgcactgacgggtgcccccctgaacctgaccccagagaccggcttactaaaagccagataacagtatgcgtatttgcgcgctgatttttgcggtataagaatatatactgatatgtatacccgaagtatgtcaaaaagaggtatgctatgaagcagcgtattacagtgacagttgacagcgacagctatcagttgctcaaggcatatatgatgtcaatatctccggtctggtaagcacaaccatgcagaatgaagcccgtcgtctgcgtgccgaacgctggaaagcggaaaatcaggaagggatggctgaggtcgcccggtttattgaaatgaacggctcttttgctgacgagaacaggggctggtgaaatgcagtttaaggtttacacctataaaagagagagccgttatcgtctgtttgtggatgtacagagtgatattattgacacgcccgggcgacggatggtgatccccctggccagtgcacgtctgctgtcagataaagtctcccgtgaactttacccggtggtgcatatcggggatgaaagctggcgcatgatgaccaccgatatggccagtgtgccggtgtccgttatcggggaagaagtggctgatctcagccaccgcgaaaatgacatcaaaaacgccattaacctgatgttctggggaatataaatgtcaggctcccttatacacagccagggtctctcgcgttgaccaacgaccacctcgtcgccttggcctgcctcggcggacgtcctgcgctggatgcagtgaaaaagggattgggaggctccccaaccccctaccctaactatgccaatgcaggacacgtggagggacagagcgccctgttcatgcgggataacggcatctccgagggcctggtgttccacaacaatcccgagggcacctgcggcttttgcgtgaacatgaccgagacactgctgcccgagaatgccaagatgacagtggtgccacctgagggagcaatccctgtgaagagaggcgccaccggcgagacaaaggtgtttaccggcaactctaatagccctaagtccccaacaaagggcggctgctctggaggcagcaccaacctgtctgacatcatcgagaaggagacaggcaagcagctggtcatccaggagagcatcctgatgctgcccgaagaagtcgaagaagtgatcggaaacaagcctgagagcgatatcctggtccataccgcctacgacgagagtaccgacgaaaatgtgatgctgctgacatccgacgccccagagtataagccctgggctctggtcatccaggattccaacggagagaacaaaatcaaaatgctg

3)MTS-G1397N

atgttggggtttgtgggtcgggtggccgctgctccggcctccggggccttgcggagactcaccccttcagcgtcgctgcccccagctcagctcttactgcgggccgctccgacggcggtccatcctgtcagggactatgcggcgcaaacatctgagagcggcggaggcgggagccccggcgcggccgctgactacaaggatgacgacgataaaggtagcgtggatctacgcacgctcggctacagccagcagcaacaggagaagatcaaaccgaaggttcgttcgacagtggcgcagcaccacgaggcactggtcggccatgggtttacacacgcgcacatcgttgcgctcagccaacacccggcagcgttagggaccgtcgctgtcaagtatcaggacatgatcgcagcgttgccagaggcgacacacgaagcgatcgttggcgtcggcaaacagtggtccggcgcacgcgctctggaggccttgctcacggtggcgggagagttgagaggtccaccgttacagttggacacaggccaacttctcaagattgcaaaacgtggcggcgtgaccgcagtggaggcagtgcatgcatggcgcaatgcactgacgggtgcccccctgaacctgaccccagagaccggcttactaaaagccagataacagtatgcgtatttgcgcgctgatttttgcggtataagaatatatactgatatgtatacccgaagtatgtcaaaaagaggtatgctatgaagcagcgtattacagtgacagttgacagcgacagctatcagttgctcaaggcatatatgatgtcaatatctccggtctggtaagcacaaccatgcagaatgaagcccgtcgtctgcgtgccgaacgctggaaagcggaaaatcaggaagggatggctgaggtcgcccggtttattgaaatgaacggctcttttgctgacgagaacaggggctggtgaaatgcagtttaaggtttacacctataaaagagagagccgttatcgtctgtttgtggatgtacagagtgatattattgacacgcccgggcgacggatggtgatccccctggccagtgcacgtctgctgtcagataaagtctcccgtgaactttacccggtggtgcatatcggggatgaaagctggcgcatgatgaccaccgatatggccagtgtgccggtgtccgttatcggggaagaagtggctgatctcagccaccgcgaaaatgacatcaaaaacgccattaacctgatgttctggggaatataaatgtcaggctcccttatacacagccagggtctctcgcgttgaccaacgaccacctcgtcgccttggcctgcctcggcggacgtcctgcgctggatgcagtgaaaaagggattgggaggctccggctcctacgccctgggcccatatcagatctctgccccacagctgccagcatacaacggacagaccgtgggcacattctactatgtgaatgacgccggcggcctggagtctaaggtgtttagctccggcggcccaaccccctaccctaactatgccaatgcaggacacgtggagggacagagcgccctgttcatgcgggataacggcatctccgagggcctggtgttccacaacaatcccgagggcacctgcggcttttgcgtgaacatgaccgagacactgctgcccgagaatgccaagatgacagtggtgccacctgagggatctggaggcagcaccaacctgtctgacatcatcgagaaggagacaggcaagcagctggtcatccaggagagcatcctgatgctgcccgaagaagtcgaagaagtgatcggaaacaagcctgagagcgatatcctggtccataccgcctacgacgagagtaccgacgaaaatgtgatgctgctgacatccgacgccccagagtataagccctgggctctggtcatccaggattccaacggagagaacaaaatcaaaatgctg

4）MTS-1397C

atgttggggtttgtgggtcgggtggccgctgctccggcctccggggccttgcggagactcaccccttcagcgtcgctgcccccagctcagctcttactgcgggccgctccgacggcggtccatcctgtcagggactatgcggcgcaaacatctgagagcggcggaggcgggagccccggcgcggccgctgactacaaggatgacgacgataaaggtagcgtggatctacgcacgctcggctacagccagcagcaacaggagaagatcaaaccgaaggttcgttcgacagtggcgcagcaccacgaggcactggtcggccatgggtttacacacgcgcacatcgttgcgctcagccaacacccggcagcgttagggaccgtcgctgtcaagtatcaggacatgatcgcagcgttgccagaggcgacacacgaagcgatcgttggcgtcggcaaacagtggtccggcgcacgcgctctggaggccttgctcacggtggcgggagagttgagaggtccaccgttacagttggacacaggccaacttctcaagattgcaaaacgtggcggcgtgaccgcagtggaggcagtgcatgcatggcgcaatgcactgacgggtgcccccctgaacctgaccccagagaccggcttactaaaagccagataacagtatgcgtatttgcgcgctgatttttgcggtataagaatatatactgatatgtatacccgaagtatgtcaaaaagaggtatgctatgaagcagcgtattacagtgacagttgacagcgacagctatcagttgctcaaggcatatatgatgtcaatatctccggtctggtaagcacaaccatgcagaatgaagcccgtcgtctgcgtgccgaacgctggaaagcggaaaatcaggaagggatggctgaggtcgcccggtttattgaaatgaacggctcttttgctgacgagaacaggggctggtgaaatgcagtttaaggtttacacctataaaagagagagccgttatcgtctgtttgtggatgtacagagtgatattattgacacgcccgggcgacggatggtgatccccctggccagtgcacgtctgctgtcagataaagtctcccgtgaactttacccggtggtgcatatcggggatgaaagctggcgcatgatgaccaccgatatggccagtgtgccggtgtccgttatcggggaagaagtggctgatctcagccaccgcgaaaatgacatcaaaaacgccattaacctgatgttctggggaatataaatgtcaggctcccttatacacagccagggtctctcgcgttgaccaacgaccacctcgtcgccttggcctgcctcggcggacgtcctgcgctggatgcagtgaaaaagggattgggaggctccgcaatccctgtgaagagaggcgccaccggcgagacaaaggtgtttaccggcaactctaatagccctaagtccccaacaaagggcggctgctctggaggcagcaccaacctgtctgacatcatcgagaaggagacaggcaagcagctggtcatccaggagagcatcctgatgctgcccgaagaagtcgaagaagtgatcggaaacaagcctgagagcgatatcctggtccataccgcctacgacgagagtaccgacgaaaatgtgatgctgctgacatccgacgccccagagtataagccctgggctctggtcatccaggattccaacggagagaacaaaatcaaaatgctg

5）NLS-G1333N

ccaaagaagaagcgtaaggtagactacaaagaccatgacggtgattataaagatcatgacatcgattacaaggatgacgatgacaagggtaccgtggatctacgcacgctcggctacagccagcagcaacaggagaagatcaaaccgaaggttcgttcgacagtggcgcagcaccacgaggcactggtcggccatgggtttacacacgcgcacatcgttgcgctcagccaacacccggcagcgttagggaccgtcgctgtcaagtatcaggacatgatcgcagcgttgccagaggcgacacacgaagcgatcgttggcgtcggcaaacggggcgccggcgcacgcgctctggaggccttgctcacggtggcgggagagttgagaggtccaccgttacagttggacacaggccaacttctcaagattgcaaaacgtggcggcgtgaccgcagtggaggcagtgcatgcatggcgcaatgcactgacgggtgcccccctgaacctgaccccagagaccggcttactaaaagccagataacagtatgcgtatttgcgcgctgatttttgcggtataagaatatatactgatatgtatacccgaagtatgtcaaaaagaggtatgctatgaagcagcgtattacagtgacagttgacagcgacagctatcagttgctcaaggcatatatgatgtcaatatctccggtctggtaagcacaaccatgcagaatgaagcccgtcgtctgcgtgccgaacgctggaaagcggaaaatcaggaagggatggctgaggtcgcccggtttattgaaatgaacggctcttttgctgacgagaacaggggctggtgaaatgcagtttaaggtttacacctataaaagagagagccgttatcgtctgtttgtggatgtacagagtgatattattgacacgcccgggcgacggatggtgatccccctggccagtgcacgtctgctgtcagataaagtctcccgtgaactttacccggtggtgcatatcggggatgaaagctggcgcatgatgaccaccgatatggccagtgtgccggtgtccgttatcggggaagaagtggctgatctcagccaccgcgaaaatgacatcaaaaacgccattaacctgatgttctggggaatataaatgtcaggctcccttatacacagccagggtctctcgcgttgaccaacgaccacctcgtcgccttggcctgcctcggcggacgtcctgcgctggatgcagtgaaaaagggattgggaggctccggctcctacgccctgggcccatatcagatctctgccccacagctgccagcatacaacggacagaccgtgggcacattctactatgtgaatgacgccggcggcctggagtctaaggtgtttagctccggcggctctggaggcagcaccaacctgtctgacatcatcgagaaggagacaggcaagcagctggtcatccaggagagcatcctgatgctgcccgaagaagtcgaagaagtgatcggaaacaagcctgagagcgatatcctggtccataccgcctacgacgagagtaccgacgaaaatgtgatgctgctgacatccgacgccccagagtataagccctgggctctggtcatccaggattccaacggagagaacaaaatcaaaatgctg

6）NLS-G1333C

ccaaagaagaagcgtaaggtagactacaaagaccatgacggtgattataaagatcatgacatcgattacaaggatgacgatgacaagggtaccgtggatctacgcacgctcggctacagccagcagcaacaggagaagatcaaaccgaaggttcgttcgacagtggcgcagcaccacgaggcactggtcggccatgggtttacacacgcgcacatcgttgcgctcagccaacacccggcagcgttagggaccgtcgctgtcaagtatcaggacatgatcgcagcgttgccagaggcgacacacgaagcgatcgttggcgtcggcaaacggggcgccggcgcacgcgctctggaggccttgctcacggtggcgggagagttgagaggtccaccgttacagttggacacaggccaacttctcaagattgcaaaacgtggcggcgtgaccgcagtggaggcagtgcatgcatggcgcaatgcactgacgggtgcccccctgaacctgaccccagagaccggcttactaaaagccagataacagtatgcgtatttgcgcgctgatttttgcggtataagaatatatactgatatgtatacccgaagtatgtcaaaaagaggtatgctatgaagcagcgtattacagtgacagttgacagcgacagctatcagttgctcaaggcatatatgatgtcaatatctccggtctggtaagcacaaccatgcagaatgaagcccgtcgtctgcgtgccgaacgctggaaagcggaaaatcaggaagggatggctgaggtcgcccggtttattgaaatgaacggctcttttgctgacgagaacaggggctggtgaaatgcagtttaaggtttacacctataaaagagagagccgttatcgtctgtttgtggatgtacagagtgatattattgacacgcccgggcgacggatggtgatccccctggccagtgcacgtctgctgtcagataaagtctcccgtgaactttacccggtggtgcatatcggggatgaaagctggcgcatgatgaccaccgatatggccagtgtgccggtgtccgttatcggggaagaagtggctgatctcagccaccgcgaaaatgacatcaaaaacgccattaacctgatgttctggggaatataaatgtcaggctcccttatacacagccagggtctctcgcgttgaccaacgaccacctcgtcgccttggcctgcctcggcggacgtcctgcgctggatgcagtgaaaaagggattgggaggctccccaaccccctaccctaactatgccaatgcaggacacgtggagggacagagcgccctgttcatgcgggataacggcatctccgagggcctggtgttccacaacaatcccgagggcacctgcggcttttgcgtgaacatgaccgagacactgctgcccgagaatgccaagatgacagtggtgccacctgagggagcaatccctgtgaagagaggcgccaccggcgagacaaaggtgtttaccggcaactctaatagccctaagtccccaacaaagggcggctgctctggaggcagcaccaacctgtctgacatcatcgagaaggagacaggcaagcagctggtcatccaggagagcatcctgatgctgcccgaagaagtcgaagaagtgatcggaaacaagcctgagagcgatatcctggtccataccgcctacgacgagagtaccgacgaaaatgtgatgctgctgacatccgacgccccagagtataagccctgggctctggtcatccaggattccaacggagagaacaaaatcaaaatgctg

7）NLS-G1397N

ccaaagaagaagcgtaaggtagactacaaagaccatgacggtgattataaagatcatgacatcgattacaaggatgacgatgacaagggtaccgtggatctacgcacgctcggctacagccagcagcaacaggagaagatcaaaccgaaggttcgttcgacagtggcgcagcaccacgaggcactggtcggccatgggtttacacacgcgcacatcgttgcgctcagccaacacccggcagcgttagggaccgtcgctgtcaagtatcaggacatgatcgcagcgttgccagaggcgacacacgaagcgatcgttggcgtcggcaaacggggcgccggcgcacgcgctctggaggccttgctcacggtggcgggagagttgagaggtccaccgttacagttggacacaggccaacttctcaagattgcaaaacgtggcggcgtgaccgcagtggaggcagtgcatgcatggcgcaatgcactgacgggtgcccccctgaacctgaccccagagaccggcttactaaaagccagataacagtatgcgtatttgcgcgctgatttttgcggtataagaatatatactgatatgtatacccgaagtatgtcaaaaagaggtatgctatgaagcagcgtattacagtgacagttgacagcgacagctatcagttgctcaaggcatatatgatgtcaatatctccggtctggtaagcacaaccatgcagaatgaagcccgtcgtctgcgtgccgaacgctggaaagcggaaaatcaggaagggatggctgaggtcgcccggtttattgaaatgaacggctcttttgctgacgagaacaggggctggtgaaatgcagtttaaggtttacacctataaaagagagagccgttatcgtctgtttgtggatgtacagagtgatattattgacacgcccgggcgacggatggtgatccccctggccagtgcacgtctgctgtcagataaagtctcccgtgaactttacccggtggtgcatatcggggatgaaagctggcgcatgatgaccaccgatatggccagtgtgccggtgtccgttatcggggaagaagtggctgatctcagccaccgcgaaaatgacatcaaaaacgccattaacctgatgttctggggaatataaatgtcaggctcccttatacacagccagggtctctcgcgttgaccaacgaccacctcgtcgccttggcctgcctcggcggacgtcctgcgctggatgcagtgaaaaagggattgggaggctccggctcctacgccctgggcccatatcagatctctgccccacagctgccagcatacaacggacagaccgtgggcacattctactatgtgaatgacgccggcggcctggagtctaaggtgtttagctccggcggcccaaccccctaccctaactatgccaatgcaggacacgtggagggacagagcgccctgttcatgcgggataacggcatctccgagggcctggtgttccacaacaatcccgagggcacctgcggcttttgcgtgaacatgaccgagacactgctgcccgagaatgccaagatgacagtggtgccacctgagggatctggaggcagcaccaacctgtctgacatcatcgagaaggagacaggcaagcagctggtcatccaggagagcatcctgatgctgcccgaagaagtcgaagaagtgatcggaaacaagcctgagagcgatatcctggtccataccgcctacgacgagagtaccgacgaaaatgtgatgctgctgacatccgacgccccagagtataagccctgggctctggtcatccaggattccaacggagagaacaaaatcaaaatgctg

8）NLS-1397C

ccaaagaagaagcgtaaggtagactacaaagaccatgacggtgattataaagatcatgacatcgattacaaggatgacgatgacaagggtaccgtggatctacgcacgctcggctacagccagcagcaacaggagaagatcaaaccgaaggttcgttcgacagtggcgcagcaccacgaggcactggtcggccatgggtttacacacgcgcacatcgttgcgctcagccaacacccggcagcgttagggaccgtcgctgtcaagtatcaggacatgatcgcagcgttgccagaggcgacacacgaagcgatcgttggcgtcggcaaacggggcgccggcgcacgcgctctggaggccttgctcacggtggcgggagagttgagaggtccaccgttacagttggacacaggccaacttctcaagattgcaaaacgtggcggcgtgaccgcagtggaggcagtgcatgcatggcgcaatgcactgacgggtgcccccctgaacctgaccccagagaccggcttactaaaagccagataacagtatgcgtatttgcgcgctgatttttgcggtataagaatatatactgatatgtatacccgaagtatgtcaaaaagaggtatgctatgaagcagcgtattacagtgacagttgacagcgacagctatcagttgctcaaggcatatatgatgtcaatatctccggtctggtaagcacaaccatgcagaatgaagcccgtcgtctgcgtgccgaacgctggaaagcggaaaatcaggaagggatggctgaggtcgcccggtttattgaaatgaacggctcttttgctgacgagaacaggggctggtgaaatgcagtttaaggtttacacctataaaagagagagccgttatcgtctgtttgtggatgtacagagtgatattattgacacgcccgggcgacggatggtgatccccctggccagtgcacgtctgctgtcagataaagtctcccgtgaactttacccggtggtgcatatcggggatgaaagctggcgcatgatgaccaccgatatggccagtgtgccggtgtccgttatcggggaagaagtggctgatctcagccaccgcgaaaatgacatcaaaaacgccattaacctgatgttctggggaatataaatgtcaggctcccttatacacagccagggtctctcgcgttgaccaacgaccacctcgtcgccttggcctgcctcggcggacgtcctgcgctggatgcagtgaaaaagggattgggaggctccgcaatccctgtgaagagaggcgccaccggcgagacaaaggtgtttaccggcaactctaatagccctaagtccccaacaaagggcggctgctctggaggcagcaccaacctgtctgacatcatcgagaaggagacaggcaagcagctggtcatccaggagagcatcctgatgctgcccgaagaagtcgaagaagtgatcggaaacaagcctgagagcgatatcctggtccataccgcctacgacgagagtaccgacgaaaatgtgatgctgctgacatccgacgccccagagtataagccctgggctctggtcatccaggattccaacggagagaacaaaatcaaaatgctg

(IV) PCR amplification primers

1) Upstream primer

tgaccgcagtggaggcagtg

2) Downstream primer

Ttcactgcatccagcgcagg

Sequence listing

<110> Nanjing university of medical science

TALE assembly-based mitochondrial DNA editing system

<160> 394

<170> SIPOSequenceListing 1.0

<210> 1

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 1

Pro Glu Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala

1 5 10 15

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

20 25 30

Leu Thr Pro Asp Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys

35 40 45

Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala

50 55 60

His Gly Leu Thr Pro Asp

65 70

<210> 2

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 2

Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu

1 5 10 15

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

20 25 30

Pro Asp Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala

35 40 45

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

50 55 60

Leu Thr Pro Asp Gln Val

65 70

<210> 3

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 3

Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Asp Gln Val

65

<210> 4

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 4

Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Asp Gln Val Val

65

<210> 5

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 5

Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

1 5 10 15

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln

20 25 30

Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr

35 40 45

Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro

50 55 60

Asp Gln Val Val Ala

65

<210> 6

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 6

Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

1 5 10 15

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val

20 25 30

Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val

35 40 45

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp

50 55 60

Gln Val Val Ala Ile

65

<210> 7

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 7

Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu

1 5 10 15

Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val

20 25 30

Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

35 40 45

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln

50 55 60

Val Val Ala Ile Ala

65

<210> 8

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 8

Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 9

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 9

Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 10

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 10

Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val

50 55 60

Val Ala Ile Ala Ser

65

<210> 11

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 11

Pro Glu Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala

1 5 10 15

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

20 25 30

Leu Thr Pro Asp Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys

35 40 45

Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala

50 55 60

His Gly Leu Thr Pro Ala

65 70

<210> 12

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 12

Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu

1 5 10 15

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

20 25 30

Pro Asp Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala

35 40 45

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

50 55 60

Leu Thr Pro Ala Gln Val

65 70

<210> 13

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 13

Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp

20 25 30

Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Ala Gln Val

65

<210> 14

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 14

Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp

20 25 30

Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Ala Gln Val Val

65

<210> 15

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 15

Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

1 5 10 15

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln

20 25 30

Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr

35 40 45

Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro

50 55 60

Ala Gln Val Val Ala

65

<210> 16

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 16

Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

1 5 10 15

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val

20 25 30

Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val

35 40 45

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala

50 55 60

Gln Val Val Ala Ile

65

<210> 17

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 17

Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu

1 5 10 15

Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val

20 25 30

Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

35 40 45

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln

50 55 60

Val Val Ala Ile Ala

65

<210> 18

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 18

Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala

20 25 30

Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 19

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 19

Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala

20 25 30

Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 20

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 20

Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala

20 25 30

Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val

50 55 60

Val Ala Ile Ala Ser

65

<210> 21

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 21

Pro Glu Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala

1 5 10 15

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

20 25 30

Leu Thr Pro Asp Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys

35 40 45

Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala

50 55 60

His Gly Leu Thr Pro Glu

65 70

<210> 22

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 22

Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu

1 5 10 15

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

20 25 30

Pro Asp Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala

35 40 45

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

50 55 60

Leu Thr Pro Glu Gln Val

65 70

<210> 23

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 23

Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Glu Gln Val

65

<210> 24

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 24

Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Glu Gln Val Val

65

<210> 25

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 25

Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

1 5 10 15

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln

20 25 30

Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr

35 40 45

Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro

50 55 60

Glu Gln Val Val Ala

65

<210> 26

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 26

Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

1 5 10 15

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val

20 25 30

Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val

35 40 45

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

50 55 60

Gln Val Val Ala Ile

65

<210> 27

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 27

Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu

1 5 10 15

Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val

20 25 30

Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

35 40 45

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln

50 55 60

Val Val Ala Ile Ala

65

<210> 28

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 28

Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 29

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 29

Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 30

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 30

Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala Ser

65

<210> 31

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 31

Pro Glu Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala

1 5 10 15

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

20 25 30

Leu Thr Pro Asp Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys

35 40 45

Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala

50 55 60

His Gly Leu Thr Pro Glu

65 70

<210> 32

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 32

Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu

1 5 10 15

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

20 25 30

Pro Asp Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala

35 40 45

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

50 55 60

Leu Thr Pro Glu Gln Val

65 70

<210> 33

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 33

Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Glu Gln Val

65

<210> 34

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 34

Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Glu Gln Val Val

65

<210> 35

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 35

Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

1 5 10 15

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln

20 25 30

Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr

35 40 45

Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro

50 55 60

Glu Gln Val Val Ala

65

<210> 36

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 36

Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

1 5 10 15

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val

20 25 30

Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val

35 40 45

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

50 55 60

Gln Val Val Ala Ile

65

<210> 37

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 37

Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu

1 5 10 15

Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val

20 25 30

Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

35 40 45

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln

50 55 60

Val Val Ala Ile Ala

65

<210> 38

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 38

Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 39

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 39

Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 40

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 40

Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala Ser

65

<210> 41

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 41

Pro Glu Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala

1 5 10 15

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

20 25 30

Leu Thr Pro Ala Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys

35 40 45

Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala

50 55 60

His Gly Leu Thr Pro Asp

65 70

<210> 42

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 42

Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu

1 5 10 15

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

20 25 30

Pro Ala Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala

35 40 45

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

50 55 60

Leu Thr Pro Asp Gln Val

65 70

<210> 43

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 43

Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Asp Gln Val

65

<210> 44

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 44

Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Asp Gln Val Val

65

<210> 45

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 45

Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

1 5 10 15

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln

20 25 30

Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr

35 40 45

Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro

50 55 60

Asp Gln Val Val Ala

65

<210> 46

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 46

Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

1 5 10 15

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val

20 25 30

Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val

35 40 45

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp

50 55 60

Gln Val Val Ala Ile

65

<210> 47

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 47

Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu

1 5 10 15

Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val

20 25 30

Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

35 40 45

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln

50 55 60

Val Val Ala Ile Ala

65

<210> 48

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 48

Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 49

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 49

Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 50

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 50

Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val

50 55 60

Val Ala Ile Ala Ser

65

<210> 51

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 51

Pro Glu Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala

1 5 10 15

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

20 25 30

Leu Thr Pro Ala Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys

35 40 45

Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala

50 55 60

His Gly Leu Thr Pro Ala

65 70

<210> 52

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 52

Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu

1 5 10 15

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

20 25 30

Pro Ala Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala

35 40 45

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

50 55 60

Leu Thr Pro Ala Gln Val

65 70

<210> 53

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 53

Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala

20 25 30

Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Ala Gln Val

65

<210> 54

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 54

Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala

20 25 30

Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Ala Gln Val Val

65

<210> 55

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 55

Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

1 5 10 15

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln

20 25 30

Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr

35 40 45

Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro

50 55 60

Ala Gln Val Val Ala

65

<210> 56

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 56

Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

1 5 10 15

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val

20 25 30

Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val

35 40 45

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala

50 55 60

Gln Val Val Ala Ile

65

<210> 57

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 57

Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu

1 5 10 15

Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val

20 25 30

Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

35 40 45

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln

50 55 60

Val Val Ala Ile Ala

65

<210> 58

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 58

Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala

20 25 30

Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 59

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 59

Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala

20 25 30

Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 60

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 60

Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala

20 25 30

Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val

50 55 60

Val Ala Ile Ala Ser

65

<210> 61

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 61

Pro Glu Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala

1 5 10 15

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

20 25 30

Leu Thr Pro Ala Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys

35 40 45

Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala

50 55 60

His Gly Leu Thr Pro Glu

65 70

<210> 62

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 62

Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu

1 5 10 15

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

20 25 30

Pro Ala Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala

35 40 45

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

50 55 60

Leu Thr Pro Glu Gln Val

65 70

<210> 63

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 63

Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Glu Gln Val

65

<210> 64

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 64

Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Glu Gln Val Val

65

<210> 65

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 65

Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

1 5 10 15

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln

20 25 30

Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr

35 40 45

Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro

50 55 60

Glu Gln Val Val Ala

65

<210> 66

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 66

Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

1 5 10 15

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val

20 25 30

Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val

35 40 45

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

50 55 60

Gln Val Val Ala Ile

65

<210> 67

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 67

Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu

1 5 10 15

Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val

20 25 30

Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

35 40 45

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln

50 55 60

Val Val Ala Ile Ala

65

<210> 68

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 68

Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 69

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 69

Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 70

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 70

Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala Ser

65

<210> 71

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 71

Pro Glu Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala

1 5 10 15

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

20 25 30

Leu Thr Pro Ala Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys

35 40 45

Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala

50 55 60

His Gly Leu Thr Pro Glu

65 70

<210> 72

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 72

Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu

1 5 10 15

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

20 25 30

Pro Ala Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala

35 40 45

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

50 55 60

Leu Thr Pro Glu Gln Val

65 70

<210> 73

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 73

Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Glu Gln Val

65

<210> 74

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 74

Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Glu Gln Val Val

65

<210> 75

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 75

Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

1 5 10 15

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln

20 25 30

Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr

35 40 45

Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro

50 55 60

Glu Gln Val Val Ala

65

<210> 76

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 76

Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

1 5 10 15

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val

20 25 30

Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val

35 40 45

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

50 55 60

Gln Val Val Ala Ile

65

<210> 77

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 77

Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu

1 5 10 15

Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val

20 25 30

Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

35 40 45

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln

50 55 60

Val Val Ala Ile Ala

65

<210> 78

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 78

Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 79

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 79

Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 80

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 80

Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala Ser

65

<210> 81

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 81

Pro Glu Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala

1 5 10 15

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

20 25 30

Leu Thr Pro Glu Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys

35 40 45

Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala

50 55 60

His Gly Leu Thr Pro Asp

65 70

<210> 82

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 82

Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu

1 5 10 15

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

20 25 30

Pro Glu Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala

35 40 45

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

50 55 60

Leu Thr Pro Asp Gln Val

65 70

<210> 83

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 83

Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Asp Gln Val

65

<210> 84

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 84

Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Asp Gln Val Val

65

<210> 85

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 85

Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

1 5 10 15

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln

20 25 30

Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr

35 40 45

Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro

50 55 60

Asp Gln Val Val Ala

65

<210> 86

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 86

Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

1 5 10 15

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

20 25 30

Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val

35 40 45

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp

50 55 60

Gln Val Val Ala Ile

65

<210> 87

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 87

Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu

1 5 10 15

Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val

20 25 30

Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

35 40 45

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln

50 55 60

Val Val Ala Ile Ala

65

<210> 88

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 88

Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 89

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 89

Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 90

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 90

Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val

50 55 60

Val Ala Ile Ala Ser

65

<210> 91

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 91

Pro Glu Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala

1 5 10 15

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

20 25 30

Leu Thr Pro Glu Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys

35 40 45

Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala

50 55 60

His Gly Leu Thr Pro Ala

65 70

<210> 92

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 92

Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu

1 5 10 15

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

20 25 30

Pro Glu Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala

35 40 45

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

50 55 60

Leu Thr Pro Ala Gln Val

65 70

<210> 93

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 93

Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

20 25 30

Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Ala Gln Val

65

<210> 94

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 94

Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

20 25 30

Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Ala Gln Val Val

65

<210> 95

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 95

Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

1 5 10 15

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln

20 25 30

Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr

35 40 45

Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro

50 55 60

Ala Gln Val Val Ala

65

<210> 96

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 96

Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

1 5 10 15

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

20 25 30

Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val

35 40 45

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala

50 55 60

Gln Val Val Ala Ile

65

<210> 97

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 97

Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu

1 5 10 15

Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val

20 25 30

Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

35 40 45

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln

50 55 60

Val Val Ala Ile Ala

65

<210> 98

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 98

Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 99

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 99

Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 100

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 100

Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val

50 55 60

Val Ala Ile Ala Ser

65

<210> 101

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 101

Pro Glu Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala

1 5 10 15

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

20 25 30

Leu Thr Pro Glu Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys

35 40 45

Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala

50 55 60

His Gly Leu Thr Pro Glu

65 70

<210> 102

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 102

Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu

1 5 10 15

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

20 25 30

Pro Glu Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala

35 40 45

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

50 55 60

Leu Thr Pro Glu Gln Val

65 70

<210> 103

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 103

Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Glu Gln Val

65

<210> 104

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 104

Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Glu Gln Val Val

65

<210> 105

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 105

Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

1 5 10 15

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln

20 25 30

Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr

35 40 45

Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro

50 55 60

Glu Gln Val Val Ala

65

<210> 106

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 106

Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

1 5 10 15

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

20 25 30

Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val

35 40 45

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

50 55 60

Gln Val Val Ala Ile

65

<210> 107

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 107

Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu

1 5 10 15

Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val

20 25 30

Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

35 40 45

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln

50 55 60

Val Val Ala Ile Ala

65

<210> 108

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 108

Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 109

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 109

Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 110

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 110

Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala Ser

65

<210> 111

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 111

Pro Glu Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala

1 5 10 15

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

20 25 30

Leu Thr Pro Glu Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys

35 40 45

Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala

50 55 60

His Gly Leu Thr Pro Glu

65 70

<210> 112

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 112

Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu

1 5 10 15

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

20 25 30

Pro Glu Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala

35 40 45

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

50 55 60

Leu Thr Pro Glu Gln Val

65 70

<210> 113

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 113

Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Glu Gln Val

65

<210> 114

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 114

Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Glu Gln Val Val

65

<210> 115

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 115

Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

1 5 10 15

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln

20 25 30

Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr

35 40 45

Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro

50 55 60

Glu Gln Val Val Ala

65

<210> 116

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 116

Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

1 5 10 15

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

20 25 30

Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val

35 40 45

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

50 55 60

Gln Val Val Ala Ile

65

<210> 117

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 117

Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu

1 5 10 15

Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val

20 25 30

Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

35 40 45

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln

50 55 60

Val Val Ala Ile Ala

65

<210> 118

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 118

Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 119

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 119

Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 120

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 120

Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala Ser

65

<210> 121

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 121

Pro Glu Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala

1 5 10 15

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

20 25 30

Leu Thr Pro Glu Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys

35 40 45

Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala

50 55 60

His Gly Leu Thr Pro Asp

65 70

<210> 122

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 122

Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu

1 5 10 15

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

20 25 30

Pro Glu Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala

35 40 45

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

50 55 60

Leu Thr Pro Asp Gln Val

65 70

<210> 123

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 123

Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Asp Gln Val

65

<210> 124

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 124

Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Asp Gln Val Val

65

<210> 125

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 125

Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

1 5 10 15

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln

20 25 30

Val Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr

35 40 45

Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro

50 55 60

Asp Gln Val Val Ala

65

<210> 126

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 126

Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

1 5 10 15

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

20 25 30

Val Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val

35 40 45

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp

50 55 60

Gln Val Val Ala Ile

65

<210> 127

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 127

Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu

1 5 10 15

Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val

20 25 30

Ala Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

35 40 45

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln

50 55 60

Val Val Ala Ile Ala

65

<210> 128

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 128

Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 129

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 129

Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 130

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 130

Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val

50 55 60

Val Ala Ile Ala Ser

65

<210> 131

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 131

Pro Glu Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala

1 5 10 15

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

20 25 30

Leu Thr Pro Glu Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys

35 40 45

Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala

50 55 60

His Gly Leu Thr Pro Ala

65 70

<210> 132

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 132

Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu

1 5 10 15

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

20 25 30

Pro Glu Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala

35 40 45

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

50 55 60

Leu Thr Pro Ala Gln Val

65 70

<210> 133

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 133

Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

20 25 30

Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Ala Gln Val

65

<210> 134

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 134

Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

20 25 30

Gln Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Ala Gln Val Val

65

<210> 135

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 135

Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

1 5 10 15

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln

20 25 30

Val Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr

35 40 45

Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro

50 55 60

Ala Gln Val Val Ala

65

<210> 136

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 136

Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

1 5 10 15

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

20 25 30

Val Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val

35 40 45

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala

50 55 60

Gln Val Val Ala Ile

65

<210> 137

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 137

Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu

1 5 10 15

Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val

20 25 30

Ala Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

35 40 45

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln

50 55 60

Val Val Ala Ile Ala

65

<210> 138

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 138

Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 139

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 139

Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 140

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 140

Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val

50 55 60

Val Ala Ile Ala Ser

65

<210> 141

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 141

Pro Glu Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala

1 5 10 15

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

20 25 30

Leu Thr Pro Glu Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys

35 40 45

Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala

50 55 60

His Gly Leu Thr Pro Glu

65 70

<210> 142

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 142

Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu

1 5 10 15

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

20 25 30

Pro Glu Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala

35 40 45

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

50 55 60

Leu Thr Pro Glu Gln Val

65 70

<210> 143

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 143

Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Glu Gln Val

65

<210> 144

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 144

Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Glu Gln Val Val

65

<210> 145

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 145

Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

1 5 10 15

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln

20 25 30

Val Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr

35 40 45

Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro

50 55 60

Glu Gln Val Val Ala

65

<210> 146

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 146

Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

1 5 10 15

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

20 25 30

Val Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val

35 40 45

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

50 55 60

Gln Val Val Ala Ile

65

<210> 147

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 147

Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu

1 5 10 15

Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val

20 25 30

Ala Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

35 40 45

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln

50 55 60

Val Val Ala Ile Ala

65

<210> 148

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 148

Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 149

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 149

Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 150

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 150

Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala Ser

65

<210> 151

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 151

Pro Glu Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala

1 5 10 15

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

20 25 30

Leu Thr Pro Glu Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys

35 40 45

Gln Ala Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala

50 55 60

His Gly Leu Thr Pro Glu

65 70

<210> 152

<211> 70

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 152

Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu

1 5 10 15

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

20 25 30

Pro Glu Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala

35 40 45

Leu Glu Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly

50 55 60

Leu Thr Pro Glu Gln Val

65 70

<210> 153

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 153

Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Glu Gln Val

65

<210> 154

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 154

Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val

1 5 10 15

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

20 25 30

Gln Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu

35 40 45

Thr Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr

50 55 60

Pro Glu Gln Val Val

65

<210> 155

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 155

Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

1 5 10 15

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln

20 25 30

Val Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr

35 40 45

Val Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro

50 55 60

Glu Gln Val Val Ala

65

<210> 156

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 156

Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

1 5 10 15

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

20 25 30

Val Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val

35 40 45

Gln Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu

50 55 60

Gln Val Val Ala Ile

65

<210> 157

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 157

Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu

1 5 10 15

Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val

20 25 30

Ala Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln

35 40 45

Arg Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln

50 55 60

Val Val Ala Ile Ala

65

<210> 158

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 158

Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 159

<211> 68

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 159

Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala

65

<210> 160

<211> 69

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 160

Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg

35 40 45

Leu Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val

50 55 60

Val Ala Ile Ala Ser

65

<210> 161

<211> 35

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 161

Ala Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu

1 5 10 15

Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val

20 25 30

Ala Ile Ala

35

<210> 162

<211> 34

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 162

Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala

20 25 30

Ile Ala

<210> 163

<211> 34

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 163

Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala

20 25 30

Ile Ala

<210> 164

<211> 35

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 164

Ser Asn Ile Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Asp Gln Val Val Ala

20 25 30

Ile Ala Ser

35

<210> 165

<211> 35

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 165

Ala Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu

1 5 10 15

Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val

20 25 30

Ala Ile Ala

35

<210> 166

<211> 34

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 166

Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala

20 25 30

Ile Ala

<210> 167

<211> 34

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 167

Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala

20 25 30

Ile Ala

<210> 168

<211> 35

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 168

Ser His Asp Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Ala Gln Val Val Ala

20 25 30

Ile Ala Ser

35

<210> 169

<211> 35

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 169

Ala Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu

1 5 10 15

Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val

20 25 30

Ala Ile Ala

35

<210> 170

<211> 34

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 170

Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala

<210> 171

<211> 34

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 171

Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala

<210> 172

<211> 35

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 172

Ser Asn Asn Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser

35

<210> 173

<211> 35

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 173

Ala Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu

1 5 10 15

Leu Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val

20 25 30

Ala Ile Ala

35

<210> 174

<211> 34

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 174

Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala

<210> 175

<211> 34

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 175

Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala

<210> 176

<211> 35

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 176

Ser Asn Gly Gly Gly Lys Gln Ala Leu Glu Thr Val Gln Arg Leu Leu

1 5 10 15

Pro Val Leu Cys Gln Ala His Gly Leu Thr Pro Glu Gln Val Val Ala

20 25 30

Ile Ala Ser

35

<210> 177

<211> 25

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 177

Ser Asn Ile Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu

1 5 10 15

Ser Arg Pro Asp Pro Ala Leu Ala Ala

20 25

<210> 178

<211> 25

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 178

Ser Asn Ile Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu

1 5 10 15

Ser Arg Pro Asp Pro Ala Leu Ala Ala

20 25

<210> 179

<211> 25

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 179

Ser Asn Ile Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu

1 5 10 15

Ser Arg Pro Asp Pro Ala Leu Ala Ala

20 25

<210> 180

<211> 27

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 180

Gly Leu Gly Gln Ile Leu Ala Ala Gly Arg Arg Trp Arg Ala Leu Leu

1 5 10 15

Pro Ser Tyr Leu Ala Leu Ile Arg Arg Trp Pro

20 25

<210> 181

<211> 25

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 181

Ser His Asp Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu

1 5 10 15

Ser Arg Pro Asp Pro Ala Leu Ala Ala

20 25

<210> 182

<211> 25

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 182

Ser His Asp Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu

1 5 10 15

Ser Arg Pro Asp Pro Ala Leu Ala Ala

20 25

<210> 183

<211> 25

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 183

Ser His Asp Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu

1 5 10 15

Ser Arg Pro Asp Pro Ala Leu Ala Ala

20 25

<210> 184

<211> 27

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 184

Gly Leu Gly His Met Thr Ala Ala Gly Arg Arg Trp Arg Ala Leu Leu

1 5 10 15

Pro Ser Tyr Leu Ala Leu Ile Arg Arg Trp Pro

20 25

<210> 185

<211> 25

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 185

Ser Asn Asn Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu

1 5 10 15

Ser Arg Pro Asp Pro Ala Leu Ala Ala

20 25

<210> 186

<211> 25

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 186

Ser Asn Asn Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu

1 5 10 15

Ser Arg Pro Asp Pro Ala Leu Ala Ala

20 25

<210> 187

<211> 25

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 187

Ser Asn Asn Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu

1 5 10 15

Ser Arg Pro Asp Pro Ala Leu Ala Ala

20 25

<210> 188

<211> 27

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 188

Gly Leu Gly Gln Thr Met Ala Ala Gly Arg Arg Trp Arg Ala Leu Leu

1 5 10 15

Pro Ser Tyr Leu Ala Leu Ile Arg Arg Trp Pro

20 25

<210> 189

<211> 25

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 189

Ser Asn Gly Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu

1 5 10 15

Ser Arg Pro Asp Pro Ala Leu Ala Ala

20 25

<210> 190

<211> 25

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 190

Ser Asn Gly Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu

1 5 10 15

Ser Arg Pro Asp Pro Ala Leu Ala Ala

20 25

<210> 191

<211> 25

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 191

Ser Asn Gly Gly Gly Arg Pro Ala Leu Glu Ser Ile Val Ala Gln Leu

1 5 10 15

Ser Arg Pro Asp Pro Ala Leu Ala Ala

20 25

<210> 192

<211> 27

<212> PRT

<213> Artificial Sequence (Artificial Sequence)

<400> 192

Gly Leu Gly Gln Met Gly Ala Ala Gly Arg Arg Trp Arg Ala Leu Leu

1 5 10 15

Pro Ser Tyr Leu Ala Leu Ile Arg Arg Trp Pro

20 25

<210> 193

<211> 1792

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 193

atgttggggt ttgtgggtcg ggtggccgct gctccggcct ccggggcctt gcggagactc 60

accccttcag cgtcgctgcc cccagctcag ctcttactgc gggccgctcc gacggcggtc 120

catcctgtca gggactatgc ggcgcaaaca tctgagagcg gcggaggcgg gagccccggc 180

gcggccgctg actacaagga tgacgacgat aaaggtagcg tggatctacg cacgctcggc 240

tacagccagc agcaacagga gaagatcaaa ccgaaggttc gttcgacagt ggcgcagcac 300

cacgaggcac tggtcggcca tgggtttaca cacgcgcaca tcgttgcgct cagccaacac 360

ccggcagcgt tagggaccgt cgctgtcaag tatcaggaca tgatcgcagc gttgccagag 420

gcgacacacg aagcgatcgt tggcgtcggc aaacagtggt ccggcgcacg cgctctggag 480

gccttgctca cggtggcggg agagttgaga ggtccaccgt tacagttgga cacaggccaa 540

cttctcaaga ttgcaaaacg tggcggcgtg accgcagtgg aggcagtgca tgcatggcgc 600

aatgcactga cgggtgcccc cctgaacctg accccagaga ccggcttact aaaagccaga 660

taacagtatg cgtatttgcg cgctgatttt tgcggtataa gaatatatac tgatatgtat 720

acccgaagta tgtcaaaaag aggtatgcta tgaagcagcg tattacagtg acagttgaca 780

gcgacagcta tcagttgctc aaggcatata tgatgtcaat atctccggtc tggtaagcac 840

aaccatgcag aatgaagccc gtcgtctgcg tgccgaacgc tggaaagcgg aaaatcagga 900

agggatggct gaggtcgccc ggtttattga aatgaacggc tcttttgctg acgagaacag 960

gggctggtga aatgcagttt aaggtttaca cctataaaag agagagccgt tatcgtctgt 1020

ttgtggatgt acagagtgat attattgaca cgcccgggcg acggatggtg atccccctgg 1080

ccagtgcacg tctgctgtca gataaagtct cccgtgaact ttacccggtg gtgcatatcg 1140

gggatgaaag ctggcgcatg atgaccaccg atatggccag tgtgccggtg tccgttatcg 1200

gggaagaagt ggctgatctc agccaccgcg aaaatgacat caaaaacgcc attaacctga 1260

tgttctgggg aatataaatg tcaggctccc ttatacacag ccagggtctc tcgcgttgac 1320

caacgaccac ctcgtcgcct tggcctgcct cggcggacgt cctgcgctgg atgcagtgaa 1380

aaagggattg ggaggctccg gctcctacgc cctgggccca tatcagatct ctgccccaca 1440

gctgccagca tacaacggac agaccgtggg cacattctac tatgtgaatg acgccggcgg 1500

cctggagtct aaggtgttta gctccggcgg ctctggaggc agcaccaacc tgtctgacat 1560

catcgagaag gagacaggca agcagctggt catccaggag agcatcctga tgctgcccga 1620

agaagtcgaa gaagtgatcg gaaacaagcc tgagagcgat atcctggtcc ataccgccta 1680

cgacgagagt accgacgaaa atgtgatgct gctgacatcc gacgccccag agtataagcc 1740

ctgggctctg gtcatccagg attccaacgg agagaacaaa atcaaaatgc tg 1792

<210> 194

<211> 1942

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 194

atgttggggt ttgtgggtcg ggtggccgct gctccggcct ccggggcctt gcggagactc 60

accccttcag cgtcgctgcc cccagctcag ctcttactgc gggccgctcc gacggcggtc 120

catcctgtca gggactatgc ggcgcaaaca tctgagagcg gcggaggcgg gagccccggc 180

gcggccgctg actacaagga tgacgacgat aaaggtagcg tggatctacg cacgctcggc 240

tacagccagc agcaacagga gaagatcaaa ccgaaggttc gttcgacagt ggcgcagcac 300

cacgaggcac tggtcggcca tgggtttaca cacgcgcaca tcgttgcgct cagccaacac 360

ccggcagcgt tagggaccgt cgctgtcaag tatcaggaca tgatcgcagc gttgccagag 420

gcgacacacg aagcgatcgt tggcgtcggc aaacagtggt ccggcgcacg cgctctggag 480

gccttgctca cggtggcggg agagttgaga ggtccaccgt tacagttgga cacaggccaa 540

cttctcaaga ttgcaaaacg tggcggcgtg accgcagtgg aggcagtgca tgcatggcgc 600

aatgcactga cgggtgcccc cctgaacctg accccagaga ccggcttact aaaagccaga 660

taacagtatg cgtatttgcg cgctgatttt tgcggtataa gaatatatac tgatatgtat 720

acccgaagta tgtcaaaaag aggtatgcta tgaagcagcg tattacagtg acagttgaca 780

gcgacagcta tcagttgctc aaggcatata tgatgtcaat atctccggtc tggtaagcac 840

aaccatgcag aatgaagccc gtcgtctgcg tgccgaacgc tggaaagcgg aaaatcagga 900

agggatggct gaggtcgccc ggtttattga aatgaacggc tcttttgctg acgagaacag 960

gggctggtga aatgcagttt aaggtttaca cctataaaag agagagccgt tatcgtctgt 1020

ttgtggatgt acagagtgat attattgaca cgcccgggcg acggatggtg atccccctgg 1080

ccagtgcacg tctgctgtca gataaagtct cccgtgaact ttacccggtg gtgcatatcg 1140

gggatgaaag ctggcgcatg atgaccaccg atatggccag tgtgccggtg tccgttatcg 1200

gggaagaagt ggctgatctc agccaccgcg aaaatgacat caaaaacgcc attaacctga 1260

tgttctgggg aatataaatg tcaggctccc ttatacacag ccagggtctc tcgcgttgac 1320

caacgaccac ctcgtcgcct tggcctgcct cggcggacgt cctgcgctgg atgcagtgaa 1380

aaagggattg ggaggctccc caacccccta ccctaactat gccaatgcag gacacgtgga 1440

gggacagagc gccctgttca tgcgggataa cggcatctcc gagggcctgg tgttccacaa 1500

caatcccgag ggcacctgcg gcttttgcgt gaacatgacc gagacactgc tgcccgagaa 1560

tgccaagatg acagtggtgc cacctgaggg agcaatccct gtgaagagag gcgccaccgg 1620

cgagacaaag gtgtttaccg gcaactctaa tagccctaag tccccaacaa agggcggctg 1680

ctctggaggc agcaccaacc tgtctgacat catcgagaag gagacaggca agcagctggt 1740

catccaggag agcatcctga tgctgcccga agaagtcgaa gaagtgatcg gaaacaagcc 1800

tgagagcgat atcctggtcc ataccgccta cgacgagagt accgacgaaa atgtgatgct 1860

gctgacatcc gacgccccag agtataagcc ctgggctctg gtcatccagg attccaacgg 1920

agagaacaaa atcaaaatgc tg 1942

<210> 195

<211> 1984

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 195

atgttggggt ttgtgggtcg ggtggccgct gctccggcct ccggggcctt gcggagactc 60

accccttcag cgtcgctgcc cccagctcag ctcttactgc gggccgctcc gacggcggtc 120

catcctgtca gggactatgc ggcgcaaaca tctgagagcg gcggaggcgg gagccccggc 180

gcggccgctg actacaagga tgacgacgat aaaggtagcg tggatctacg cacgctcggc 240

tacagccagc agcaacagga gaagatcaaa ccgaaggttc gttcgacagt ggcgcagcac 300

cacgaggcac tggtcggcca tgggtttaca cacgcgcaca tcgttgcgct cagccaacac 360

ccggcagcgt tagggaccgt cgctgtcaag tatcaggaca tgatcgcagc gttgccagag 420

gcgacacacg aagcgatcgt tggcgtcggc aaacagtggt ccggcgcacg cgctctggag 480

gccttgctca cggtggcggg agagttgaga ggtccaccgt tacagttgga cacaggccaa 540

cttctcaaga ttgcaaaacg tggcggcgtg accgcagtgg aggcagtgca tgcatggcgc 600

aatgcactga cgggtgcccc cctgaacctg accccagaga ccggcttact aaaagccaga 660

taacagtatg cgtatttgcg cgctgatttt tgcggtataa gaatatatac tgatatgtat 720

acccgaagta tgtcaaaaag aggtatgcta tgaagcagcg tattacagtg acagttgaca 780

gcgacagcta tcagttgctc aaggcatata tgatgtcaat atctccggtc tggtaagcac 840

aaccatgcag aatgaagccc gtcgtctgcg tgccgaacgc tggaaagcgg aaaatcagga 900

agggatggct gaggtcgccc ggtttattga aatgaacggc tcttttgctg acgagaacag 960

gggctggtga aatgcagttt aaggtttaca cctataaaag agagagccgt tatcgtctgt 1020

ttgtggatgt acagagtgat attattgaca cgcccgggcg acggatggtg atccccctgg 1080

ccagtgcacg tctgctgtca gataaagtct cccgtgaact ttacccggtg gtgcatatcg 1140

gggatgaaag ctggcgcatg atgaccaccg atatggccag tgtgccggtg tccgttatcg 1200

gggaagaagt ggctgatctc agccaccgcg aaaatgacat caaaaacgcc attaacctga 1260

tgttctgggg aatataaatg tcaggctccc ttatacacag ccagggtctc tcgcgttgac 1320

caacgaccac ctcgtcgcct tggcctgcct cggcggacgt cctgcgctgg atgcagtgaa 1380

aaagggattg ggaggctccg gctcctacgc cctgggccca tatcagatct ctgccccaca 1440

gctgccagca tacaacggac agaccgtggg cacattctac tatgtgaatg acgccggcgg 1500

cctggagtct aaggtgttta gctccggcgg cccaaccccc taccctaact atgccaatgc 1560

aggacacgtg gagggacaga gcgccctgtt catgcgggat aacggcatct ccgagggcct 1620

ggtgttccac aacaatcccg agggcacctg cggcttttgc gtgaacatga ccgagacact 1680

gctgcccgag aatgccaaga tgacagtggt gccacctgag ggatctggag gcagcaccaa 1740

cctgtctgac atcatcgaga aggagacagg caagcagctg gtcatccagg agagcatcct 1800

gatgctgccc gaagaagtcg aagaagtgat cggaaacaag cctgagagcg atatcctggt 1860

ccataccgcc tacgacgaga gtaccgacga aaatgtgatg ctgctgacat ccgacgcccc 1920

agagtataag ccctgggctc tggtcatcca ggattccaac ggagagaaca aaatcaaaat 1980

gctg 1984

<210> 196

<211> 1750

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 196

atgttggggt ttgtgggtcg ggtggccgct gctccggcct ccggggcctt gcggagactc 60

accccttcag cgtcgctgcc cccagctcag ctcttactgc gggccgctcc gacggcggtc 120

catcctgtca gggactatgc ggcgcaaaca tctgagagcg gcggaggcgg gagccccggc 180

gcggccgctg actacaagga tgacgacgat aaaggtagcg tggatctacg cacgctcggc 240

tacagccagc agcaacagga gaagatcaaa ccgaaggttc gttcgacagt ggcgcagcac 300

cacgaggcac tggtcggcca tgggtttaca cacgcgcaca tcgttgcgct cagccaacac 360

ccggcagcgt tagggaccgt cgctgtcaag tatcaggaca tgatcgcagc gttgccagag 420

gcgacacacg aagcgatcgt tggcgtcggc aaacagtggt ccggcgcacg cgctctggag 480

gccttgctca cggtggcggg agagttgaga ggtccaccgt tacagttgga cacaggccaa 540

cttctcaaga ttgcaaaacg tggcggcgtg accgcagtgg aggcagtgca tgcatggcgc 600

aatgcactga cgggtgcccc cctgaacctg accccagaga ccggcttact aaaagccaga 660

taacagtatg cgtatttgcg cgctgatttt tgcggtataa gaatatatac tgatatgtat 720

acccgaagta tgtcaaaaag aggtatgcta tgaagcagcg tattacagtg acagttgaca 780

gcgacagcta tcagttgctc aaggcatata tgatgtcaat atctccggtc tggtaagcac 840

aaccatgcag aatgaagccc gtcgtctgcg tgccgaacgc tggaaagcgg aaaatcagga 900

agggatggct gaggtcgccc ggtttattga aatgaacggc tcttttgctg acgagaacag 960

gggctggtga aatgcagttt aaggtttaca cctataaaag agagagccgt tatcgtctgt 1020

ttgtggatgt acagagtgat attattgaca cgcccgggcg acggatggtg atccccctgg 1080

ccagtgcacg tctgctgtca gataaagtct cccgtgaact ttacccggtg gtgcatatcg 1140

gggatgaaag ctggcgcatg atgaccaccg atatggccag tgtgccggtg tccgttatcg 1200

gggaagaagt ggctgatctc agccaccgcg aaaatgacat caaaaacgcc attaacctga 1260

tgttctgggg aatataaatg tcaggctccc ttatacacag ccagggtctc tcgcgttgac 1320

caacgaccac ctcgtcgcct tggcctgcct cggcggacgt cctgcgctgg atgcagtgaa 1380

aaagggattg ggaggctccg caatccctgt gaagagaggc gccaccggcg agacaaaggt 1440

gtttaccggc aactctaata gccctaagtc cccaacaaag ggcggctgct ctggaggcag 1500

caccaacctg tctgacatca tcgagaagga gacaggcaag cagctggtca tccaggagag 1560

catcctgatg ctgcccgaag aagtcgaaga agtgatcgga aacaagcctg agagcgatat 1620

cctggtccat accgcctacg acgagagtac cgacgaaaat gtgatgctgc tgacatccga 1680

cgccccagag tataagccct gggctctggt catccaggat tccaacggag agaacaaaat 1740

caaaatgctg 1750

<210> 197

<211> 1666

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 197

ccaaagaaga agcgtaaggt agactacaaa gaccatgacg gtgattataa agatcatgac 60

atcgattaca aggatgacga tgacaagggt accgtggatc tacgcacgct cggctacagc 120

cagcagcaac aggagaagat caaaccgaag gttcgttcga cagtggcgca gcaccacgag 180

gcactggtcg gccatgggtt tacacacgcg cacatcgttg cgctcagcca acacccggca 240

gcgttaggga ccgtcgctgt caagtatcag gacatgatcg cagcgttgcc agaggcgaca 300

cacgaagcga tcgttggcgt cggcaaacgg ggcgccggcg cacgcgctct ggaggccttg 360

ctcacggtgg cgggagagtt gagaggtcca ccgttacagt tggacacagg ccaacttctc 420

aagattgcaa aacgtggcgg cgtgaccgca gtggaggcag tgcatgcatg gcgcaatgca 480

ctgacgggtg cccccctgaa cctgacccca gagaccggct tactaaaagc cagataacag 540

tatgcgtatt tgcgcgctga tttttgcggt ataagaatat atactgatat gtatacccga 600

agtatgtcaa aaagaggtat gctatgaagc agcgtattac agtgacagtt gacagcgaca 660

gctatcagtt gctcaaggca tatatgatgt caatatctcc ggtctggtaa gcacaaccat 720

gcagaatgaa gcccgtcgtc tgcgtgccga acgctggaaa gcggaaaatc aggaagggat 780

ggctgaggtc gcccggttta ttgaaatgaa cggctctttt gctgacgaga acaggggctg 840

gtgaaatgca gtttaaggtt tacacctata aaagagagag ccgttatcgt ctgtttgtgg 900

atgtacagag tgatattatt gacacgcccg ggcgacggat ggtgatcccc ctggccagtg 960

cacgtctgct gtcagataaa gtctcccgtg aactttaccc ggtggtgcat atcggggatg 1020

aaagctggcg catgatgacc accgatatgg ccagtgtgcc ggtgtccgtt atcggggaag 1080

aagtggctga tctcagccac cgcgaaaatg acatcaaaaa cgccattaac ctgatgttct 1140

ggggaatata aatgtcaggc tcccttatac acagccaggg tctctcgcgt tgaccaacga 1200

ccacctcgtc gccttggcct gcctcggcgg acgtcctgcg ctggatgcag tgaaaaaggg 1260

attgggaggc tccggctcct acgccctggg cccatatcag atctctgccc cacagctgcc 1320

agcatacaac ggacagaccg tgggcacatt ctactatgtg aatgacgccg gcggcctgga 1380

gtctaaggtg tttagctccg gcggctctgg aggcagcacc aacctgtctg acatcatcga 1440

gaaggagaca ggcaagcagc tggtcatcca ggagagcatc ctgatgctgc ccgaagaagt 1500

cgaagaagtg atcggaaaca agcctgagag cgatatcctg gtccataccg cctacgacga 1560

gagtaccgac gaaaatgtga tgctgctgac atccgacgcc ccagagtata agccctgggc 1620

tctggtcatc caggattcca acggagagaa caaaatcaaa atgctg 1666

<210> 198

<211> 1816

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 198

ccaaagaaga agcgtaaggt agactacaaa gaccatgacg gtgattataa agatcatgac 60

atcgattaca aggatgacga tgacaagggt accgtggatc tacgcacgct cggctacagc 120

cagcagcaac aggagaagat caaaccgaag gttcgttcga cagtggcgca gcaccacgag 180

gcactggtcg gccatgggtt tacacacgcg cacatcgttg cgctcagcca acacccggca 240

gcgttaggga ccgtcgctgt caagtatcag gacatgatcg cagcgttgcc agaggcgaca 300

cacgaagcga tcgttggcgt cggcaaacgg ggcgccggcg cacgcgctct ggaggccttg 360

ctcacggtgg cgggagagtt gagaggtcca ccgttacagt tggacacagg ccaacttctc 420

aagattgcaa aacgtggcgg cgtgaccgca gtggaggcag tgcatgcatg gcgcaatgca 480

ctgacgggtg cccccctgaa cctgacccca gagaccggct tactaaaagc cagataacag 540

tatgcgtatt tgcgcgctga tttttgcggt ataagaatat atactgatat gtatacccga 600

agtatgtcaa aaagaggtat gctatgaagc agcgtattac agtgacagtt gacagcgaca 660

gctatcagtt gctcaaggca tatatgatgt caatatctcc ggtctggtaa gcacaaccat 720

gcagaatgaa gcccgtcgtc tgcgtgccga acgctggaaa gcggaaaatc aggaagggat 780

ggctgaggtc gcccggttta ttgaaatgaa cggctctttt gctgacgaga acaggggctg 840

gtgaaatgca gtttaaggtt tacacctata aaagagagag ccgttatcgt ctgtttgtgg 900

atgtacagag tgatattatt gacacgcccg ggcgacggat ggtgatcccc ctggccagtg 960

cacgtctgct gtcagataaa gtctcccgtg aactttaccc ggtggtgcat atcggggatg 1020

aaagctggcg catgatgacc accgatatgg ccagtgtgcc ggtgtccgtt atcggggaag 1080

aagtggctga tctcagccac cgcgaaaatg acatcaaaaa cgccattaac ctgatgttct 1140

ggggaatata aatgtcaggc tcccttatac acagccaggg tctctcgcgt tgaccaacga 1200

ccacctcgtc gccttggcct gcctcggcgg acgtcctgcg ctggatgcag tgaaaaaggg 1260

attgggaggc tccccaaccc cctaccctaa ctatgccaat gcaggacacg tggagggaca 1320

gagcgccctg ttcatgcggg ataacggcat ctccgagggc ctggtgttcc acaacaatcc 1380

cgagggcacc tgcggctttt gcgtgaacat gaccgagaca ctgctgcccg agaatgccaa 1440

gatgacagtg gtgccacctg agggagcaat ccctgtgaag agaggcgcca ccggcgagac 1500

aaaggtgttt accggcaact ctaatagccc taagtcccca acaaagggcg gctgctctgg 1560

aggcagcacc aacctgtctg acatcatcga gaaggagaca ggcaagcagc tggtcatcca 1620

ggagagcatc ctgatgctgc ccgaagaagt cgaagaagtg atcggaaaca agcctgagag 1680

cgatatcctg gtccataccg cctacgacga gagtaccgac gaaaatgtga tgctgctgac 1740

atccgacgcc ccagagtata agccctgggc tctggtcatc caggattcca acggagagaa 1800

caaaatcaaa atgctg 1816

<210> 199

<211> 1858

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 199

ccaaagaaga agcgtaaggt agactacaaa gaccatgacg gtgattataa agatcatgac 60

atcgattaca aggatgacga tgacaagggt accgtggatc tacgcacgct cggctacagc 120

cagcagcaac aggagaagat caaaccgaag gttcgttcga cagtggcgca gcaccacgag 180

gcactggtcg gccatgggtt tacacacgcg cacatcgttg cgctcagcca acacccggca 240

gcgttaggga ccgtcgctgt caagtatcag gacatgatcg cagcgttgcc agaggcgaca 300

cacgaagcga tcgttggcgt cggcaaacgg ggcgccggcg cacgcgctct ggaggccttg 360

ctcacggtgg cgggagagtt gagaggtcca ccgttacagt tggacacagg ccaacttctc 420

aagattgcaa aacgtggcgg cgtgaccgca gtggaggcag tgcatgcatg gcgcaatgca 480

ctgacgggtg cccccctgaa cctgacccca gagaccggct tactaaaagc cagataacag 540

tatgcgtatt tgcgcgctga tttttgcggt ataagaatat atactgatat gtatacccga 600

agtatgtcaa aaagaggtat gctatgaagc agcgtattac agtgacagtt gacagcgaca 660

gctatcagtt gctcaaggca tatatgatgt caatatctcc ggtctggtaa gcacaaccat 720

gcagaatgaa gcccgtcgtc tgcgtgccga acgctggaaa gcggaaaatc aggaagggat 780

ggctgaggtc gcccggttta ttgaaatgaa cggctctttt gctgacgaga acaggggctg 840

gtgaaatgca gtttaaggtt tacacctata aaagagagag ccgttatcgt ctgtttgtgg 900

atgtacagag tgatattatt gacacgcccg ggcgacggat ggtgatcccc ctggccagtg 960

cacgtctgct gtcagataaa gtctcccgtg aactttaccc ggtggtgcat atcggggatg 1020

aaagctggcg catgatgacc accgatatgg ccagtgtgcc ggtgtccgtt atcggggaag 1080

aagtggctga tctcagccac cgcgaaaatg acatcaaaaa cgccattaac ctgatgttct 1140

ggggaatata aatgtcaggc tcccttatac acagccaggg tctctcgcgt tgaccaacga 1200

ccacctcgtc gccttggcct gcctcggcgg acgtcctgcg ctggatgcag tgaaaaaggg 1260

attgggaggc tccggctcct acgccctggg cccatatcag atctctgccc cacagctgcc 1320

agcatacaac ggacagaccg tgggcacatt ctactatgtg aatgacgccg gcggcctgga 1380

gtctaaggtg tttagctccg gcggcccaac cccctaccct aactatgcca atgcaggaca 1440

cgtggaggga cagagcgccc tgttcatgcg ggataacggc atctccgagg gcctggtgtt 1500

ccacaacaat cccgagggca cctgcggctt ttgcgtgaac atgaccgaga cactgctgcc 1560

cgagaatgcc aagatgacag tggtgccacc tgagggatct ggaggcagca ccaacctgtc 1620

tgacatcatc gagaaggaga caggcaagca gctggtcatc caggagagca tcctgatgct 1680

gcccgaagaa gtcgaagaag tgatcggaaa caagcctgag agcgatatcc tggtccatac 1740

cgcctacgac gagagtaccg acgaaaatgt gatgctgctg acatccgacg ccccagagta 1800

taagccctgg gctctggtca tccaggattc caacggagag aacaaaatca aaatgctg 1858

<210> 200

<211> 1624

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 200

ccaaagaaga agcgtaaggt agactacaaa gaccatgacg gtgattataa agatcatgac 60

atcgattaca aggatgacga tgacaagggt accgtggatc tacgcacgct cggctacagc 120

cagcagcaac aggagaagat caaaccgaag gttcgttcga cagtggcgca gcaccacgag 180

gcactggtcg gccatgggtt tacacacgcg cacatcgttg cgctcagcca acacccggca 240

gcgttaggga ccgtcgctgt caagtatcag gacatgatcg cagcgttgcc agaggcgaca 300

cacgaagcga tcgttggcgt cggcaaacgg ggcgccggcg cacgcgctct ggaggccttg 360

ctcacggtgg cgggagagtt gagaggtcca ccgttacagt tggacacagg ccaacttctc 420

aagattgcaa aacgtggcgg cgtgaccgca gtggaggcag tgcatgcatg gcgcaatgca 480

ctgacgggtg cccccctgaa cctgacccca gagaccggct tactaaaagc cagataacag 540

tatgcgtatt tgcgcgctga tttttgcggt ataagaatat atactgatat gtatacccga 600

agtatgtcaa aaagaggtat gctatgaagc agcgtattac agtgacagtt gacagcgaca 660

gctatcagtt gctcaaggca tatatgatgt caatatctcc ggtctggtaa gcacaaccat 720

gcagaatgaa gcccgtcgtc tgcgtgccga acgctggaaa gcggaaaatc aggaagggat 780

ggctgaggtc gcccggttta ttgaaatgaa cggctctttt gctgacgaga acaggggctg 840

gtgaaatgca gtttaaggtt tacacctata aaagagagag ccgttatcgt ctgtttgtgg 900

atgtacagag tgatattatt gacacgcccg ggcgacggat ggtgatcccc ctggccagtg 960

cacgtctgct gtcagataaa gtctcccgtg aactttaccc ggtggtgcat atcggggatg 1020

aaagctggcg catgatgacc accgatatgg ccagtgtgcc ggtgtccgtt atcggggaag 1080

aagtggctga tctcagccac cgcgaaaatg acatcaaaaa cgccattaac ctgatgttct 1140

ggggaatata aatgtcaggc tcccttatac acagccaggg tctctcgcgt tgaccaacga 1200

ccacctcgtc gccttggcct gcctcggcgg acgtcctgcg ctggatgcag tgaaaaaggg 1260

attgggaggc tccgcaatcc ctgtgaagag aggcgccacc ggcgagacaa aggtgtttac 1320

cggcaactct aatagcccta agtccccaac aaagggcggc tgctctggag gcagcaccaa 1380

cctgtctgac atcatcgaga aggagacagg caagcagctg gtcatccagg agagcatcct 1440

gatgctgccc gaagaagtcg aagaagtgat cggaaacaag cctgagagcg atatcctggt 1500

ccataccgcc tacgacgaga gtaccgacga aaatgtgatg ctgctgacat ccgacgcccc 1560

agagtataag ccctgggctc tggtcatcca ggattccaac ggagagaaca aaatcaaaat 1620

gctg 1624

<210> 201

<211> 20

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 201

tgaccgcagt ggaggcagtg 20

<210> 202

<211> 20

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 202

ttcactgcat ccagcgcagg 20

<210> 203

<211> 216

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 203

ccccggagca ggtggtggcc atcgctagta atattggtgg caaacaggct cttgagacgg 60

ttcagcgcct ccttccagtt ctctgtcaag cccacggact caccccagat caagttgtag 120

cgattgctag taatattggt ggcaaacagg ctcttgagac ggttcagcgc ctccttccag 180

ttctctgtca agcccacgga ctcaccccag atcagg 216

<210> 204

<211> 212

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 204

caggttgtag cgattgctag taatattggt ggcaaacagg ctcttgagac ggttcagcgc 60

ctccttccag ttctctgtca agcccacgga ctcaccccag atcaagttgt agcgattgct 120

agtaatattg gtggcaaaca ggctcttgag acggttcagc gcctccttcc agttctctgt 180

caagcccacg gactcacccc agatcaagtg gt 212

<210> 205

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 205

tggtagcgat tgctagtaat attggtggca aacaggctct tgagacggtt cagcgcctcc 60

ttccagttct ctgtcaagcc cacggactca ccccagatca agttgtagcg attgctagta 120

atattggtgg caaacaggct cttgagacgg ttcagcgcct ccttccagtt ctctgtcaag 180

cccacggact caccccagat caagttgtag 210

<210> 206

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 206

gtagcgattg ctagtaatat tggtggcaaa caggctcttg agacggttca gcgcctcctt 60

ccagttctct gtcaagccca cggactcacc ccagatcaag ttgtagcgat tgctagtaat 120

attggtggca aacaggctct tgagacggtt cagcgcctcc ttccagttct ctgtcaagcc 180

cacggactca ccccagatca agttgtagca a 211

<210> 207

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 207

gcaattgcta gtaatattgg tggcaaacag gctcttgaga cggttcagcg cctccttcca 60

gttctctgtc aagcccacgg actcacccca gatcaagttg tagcgattgc tagtaatatt 120

ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg tcaagcccac 180

ggactcaccc cagatcaagt tgtagcgatt 210

<210> 208

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 208

gattgctagt aatattggtg gcaaacaggc tcttgagacg gttcagcgcc tccttccagt 60

tctctgtcaa gcccacggac tcaccccaga tcaagttgta gcgattgcta gtaatattgg 120

tggcaaacag gctcttgaga cggttcagcg cctccttcca gttctctgtc aagcccacgg 180

actcacccca gatcaagttg tagcgatagc c 211

<210> 209

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 209

agccagtaat attggtggca aacaggctct tgagacggtt cagcgcctcc ttccagttct 60

ctgtcaagcc cacggactca ccccagatca agttgtagcg attgctagta atattggtgg 120

caaacaggct cttgagacgg ttcagcgcct ccttccagtt ctctgtcaag cccacggact 180

caccccagat caagttgtag cgattgcaag t 211

<210> 210

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 210

aagtaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60

tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtaata ttggtggcaa 120

acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180

cccagatcaa gttgtagcga ttgcttcc 208

<210> 211

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 211

ttccaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60

tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtaata ttggtggcaa 120

acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180

cccagatcaa gttgtagcga ttgcctct 208

<210> 212

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 212

ctctaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60

tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtaata ttggtggcaa 120

acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180

cccagatcaa gttgtagcga ttgcgtca 208

<210> 213

<211> 216

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 213

ccccggagca ggtggtggcc atcgctagta atattggtgg caaacaggct cttgagacgg 60

ttcagcgcct ccttccagtt ctctgtcaag cccacggact caccccagat caagttgtag 120

cgattgctag tcatgacggt ggcaaacagg ctcttgaaac cgtccaacgc cttctaccag 180

ttctctgtca agcccacgga ctaaccccag cgcagg 216

<210> 214

<211> 212

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 214

caggttgtag cgattgctag taatattggt ggcaaacagg ctcttgagac ggttcagcgc 60

ctccttccag ttctctgtca agcccacgga ctcaccccag atcaagttgt agcgattgct 120

agtcatgacg gtggcaaaca ggctcttgaa accgtccaac gccttctacc agttctctgt 180

caagcccacg gactaacccc agcgcaagtg gt 212

<210> 215

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 215

tggtagcgat tgctagtaat attggtggca aacaggctct tgagacggtt cagcgcctcc 60

ttccagttct ctgtcaagcc cacggactca ccccagatca agttgtagcg attgctagtc 120

atgacggtgg caaacaggct cttgaaaccg tccaacgcct tctaccagtt ctctgtcaag 180

cccacggact aaccccagcg caagttgtag 210

<210> 216

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 216

gtagcgattg ctagtaatat tggtggcaaa caggctcttg agacggttca gcgcctcctt 60

ccagttctct gtcaagccca cggactcacc ccagatcaag ttgtagcgat tgctagtcat 120

gacggtggca aacaggctct tgaaaccgtc caacgccttc taccagttct ctgtcaagcc 180

cacggactaa ccccagcgca agttgtagca a 211

<210> 217

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 217

gcaattgcta gtaatattgg tggcaaacag gctcttgaga cggttcagcg cctccttcca 60

gttctctgtc aagcccacgg actcacccca gatcaagttg tagcgattgc tagtcatgac 120

ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg tcaagcccac 180

ggactaaccc cagcgcaagt tgtagcgatt 210

<210> 218

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 218

gattgctagt aatattggtg gcaaacaggc tcttgagacg gttcagcgcc tccttccagt 60

tctctgtcaa gcccacggac tcaccccaga tcaagttgta gcgattgcta gtcatgacgg 120

tggcaaacag gctcttgaaa ccgtccaacg ccttctacca gttctctgtc aagcccacgg 180

actaacccca gcgcaagttg tagcgatagc c 211

<210> 219

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 219

agccagtaat attggtggca aacaggctct tgagacggtt cagcgcctcc ttccagttct 60

ctgtcaagcc cacggactca ccccagatca agttgtagcg attgctagtc atgacggtgg 120

caaacaggct cttgaaaccg tccaacgcct tctaccagtt ctctgtcaag cccacggact 180

aaccccagcg caagttgtag cgattgcaag t 211

<210> 220

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 220

aagtaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60

tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtcatg acggtggcaa 120

acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180

cccagcgcaa gttgtagcga ttgcttcc 208

<210> 221

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 221

ttccaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60

tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtcatg acggtggcaa 120

acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180

cccagcgcaa gttgtagcga ttgcctct 208

<210> 222

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 222

ctctaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60

tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtcatg acggtggcaa 120

acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180

cccagcgcaa gttgtagcga ttgcgtca 208

<210> 223

<211> 216

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 223

ccccggagca ggtggtggcc atcgctagta atattggtgg caaacaggct cttgagacgg 60

ttcagcgcct ccttccagtt ctctgtcaag cccacggact caccccagat caagttgtag 120

cgattgctag taacaatggt ggcaaacagg ctcttgaaac cgtacagcgc ctactgccag 180

ttctctgtca agcccacggt ctgactccgg agcagg 216

<210> 224

<211> 212

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 224

caggttgtag cgattgctag taatattggt ggcaaacagg ctcttgagac ggttcagcgc 60

ctccttccag ttctctgtca agcccacgga ctcaccccag atcaagttgt agcgattgct 120

agtaacaatg gtggcaaaca ggctcttgaa accgtacagc gcctactgcc agttctctgt 180

caagcccacg gtctgactcc ggagcaagtg gt 212

<210> 225

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 225

tggtagcgat tgctagtaat attggtggca aacaggctct tgagacggtt cagcgcctcc 60

ttccagttct ctgtcaagcc cacggactca ccccagatca agttgtagcg attgctagta 120

acaatggtgg caaacaggct cttgaaaccg tacagcgcct actgccagtt ctctgtcaag 180

cccacggtct gactccggag caagttgtag 210

<210> 226

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 226

gtagcgattg ctagtaatat tggtggcaaa caggctcttg agacggttca gcgcctcctt 60

ccagttctct gtcaagccca cggactcacc ccagatcaag ttgtagcgat tgctagtaac 120

aatggtggca aacaggctct tgaaaccgta cagcgcctac tgccagttct ctgtcaagcc 180

cacggtctga ctccggagca agttgtagca a 211

<210> 227

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 227

gcaattgcta gtaatattgg tggcaaacag gctcttgaga cggttcagcg cctccttcca 60

gttctctgtc aagcccacgg actcacccca gatcaagttg tagcgattgc tagtaacaat 120

ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg tcaagcccac 180

ggtctgactc cggagcaagt tgtagcgatt 210

<210> 228

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 228

gattgctagt aatattggtg gcaaacaggc tcttgagacg gttcagcgcc tccttccagt 60

tctctgtcaa gcccacggac tcaccccaga tcaagttgta gcgattgcta gtaacaatgg 120

tggcaaacag gctcttgaaa ccgtacagcg cctactgcca gttctctgtc aagcccacgg 180

tctgactccg gagcaagttg tagcgatagc c 211

<210> 229

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 229

agccagtaat attggtggca aacaggctct tgagacggtt cagcgcctcc ttccagttct 60

ctgtcaagcc cacggactca ccccagatca agttgtagcg attgctagta acaatggtgg 120

caaacaggct cttgaaaccg tacagcgcct actgccagtt ctctgtcaag cccacggtct 180

gactccggag caagttgtag cgattgcaag t 211

<210> 230

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 230

aagtaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60

tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtaaca atggtggcaa 120

acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180

tccggagcaa gttgtagcga ttgcttcc 208

<210> 231

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 231

ttccaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60

tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtaaca atggtggcaa 120

acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180

tccggagcaa gttgtagcga ttgcctct 208

<210> 232

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 232

ctctaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60

tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtaaca atggtggcaa 120

acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180

tccggagcaa gttgtagcga ttgcgtca 208

<210> 233

<211> 216

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 233

ccccggagca ggtggtggcc atcgctagta atattggtgg caaacaggct cttgagacgg 60

ttcagcgcct ccttccagtt ctctgtcaag cccacggact caccccagat caagttgtag 120

cgattgctag taatgggggt ggcaaacagg ctcttgagac tgttcagcgc cttctaccag 180

ttctctgtca agcccacggc ctgacgcccg agcagg 216

<210> 234

<211> 212

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 234

caggttgtag cgattgctag taatattggt ggcaaacagg ctcttgagac ggttcagcgc 60

ctccttccag ttctctgtca agcccacgga ctcaccccag atcaagttgt agcgattgct 120

agtaatgggg gtggcaaaca ggctcttgag actgttcagc gccttctacc agttctctgt 180

caagcccacg gcctgacgcc cgagcaagtg gt 212

<210> 235

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 235

tggtagcgat tgctagtaat attggtggca aacaggctct tgagacggtt cagcgcctcc 60

ttccagttct ctgtcaagcc cacggactca ccccagatca agttgtagcg attgctagta 120

atgggggtgg caaacaggct cttgagactg ttcagcgcct tctaccagtt ctctgtcaag 180

cccacggcct gacgcccgag caagttgtag 210

<210> 236

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 236

gtagcgattg ctagtaatat tggtggcaaa caggctcttg agacggttca gcgcctcctt 60

ccagttctct gtcaagccca cggactcacc ccagatcaag ttgtagcgat tgctagtaat 120

gggggtggca aacaggctct tgagactgtt cagcgccttc taccagttct ctgtcaagcc 180

cacggcctga cgcccgagca agttgtagca a 211

<210> 237

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 237

gcaattgcta gtaatattgg tggcaaacag gctcttgaga cggttcagcg cctccttcca 60

gttctctgtc aagcccacgg actcacccca gatcaagttg tagcgattgc tagtaatggg 120

ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg tcaagcccac 180

ggcctgacgc ccgagcaagt tgtagcgatt 210

<210> 238

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 238

gattgctagt aatattggtg gcaaacaggc tcttgagacg gttcagcgcc tccttccagt 60

tctctgtcaa gcccacggac tcaccccaga tcaagttgta gcgattgcta gtaatggggg 120

tggcaaacag gctcttgaga ctgttcagcg ccttctacca gttctctgtc aagcccacgg 180

cctgacgccc gagcaagttg tagcgatagc c 211

<210> 239

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 239

agccagtaat attggtggca aacaggctct tgagacggtt cagcgcctcc ttccagttct 60

ctgtcaagcc cacggactca ccccagatca agttgtagcg attgctagta atgggggtgg 120

caaacaggct cttgagactg ttcagcgcct tctaccagtt ctctgtcaag cccacggcct 180

gacgcccgag caagttgtag cgattgcaag t 211

<210> 240

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 240

aagtaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60

tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtaatg ggggtggcaa 120

acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180

gcccgagcaa gttgtagcga ttgcttcc 208

<210> 241

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 241

ttccaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60

tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtaatg ggggtggcaa 120

acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180

gcccgagcaa gttgtagcga ttgcctct 208

<210> 242

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 242

ctctaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60

tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gctagtaatg ggggtggcaa 120

acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180

gcccgagcaa gttgtagcga ttgcgtca 208

<210> 243

<211> 216

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 243

ccccggagca ggtggtggcc atcgctagtc atgacggtgg caaacaggct cttgaaaccg 60

tccaacgcct tctaccagtt ctctgtcaag cccacggact aaccccagcg caagttgtag 120

cgattgctag taatattggt ggcaaacagg ctcttgagac ggttcagcgc ctccttccag 180

ttctctgtca agcccacgga ctcaccccag atcagg 216

<210> 244

<211> 212

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 244

caggttgtag cgattgctag tcatgacggt ggcaaacagg ctcttgaaac cgtccaacgc 60

cttctaccag ttctctgtca agcccacgga ctaaccccag cgcaagttgt agcgattgct 120

agtaatattg gtggcaaaca ggctcttgag acggttcagc gcctccttcc agttctctgt 180

caagcccacg gactcacccc agatcaagtg gt 212

<210> 245

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 245

tggtagcgat tgctagtcat gacggtggca aacaggctct tgaaaccgtc caacgccttc 60

taccagttct ctgtcaagcc cacggactaa ccccagcgca agttgtagcg attgctagta 120

atattggtgg caaacaggct cttgagacgg ttcagcgcct ccttccagtt ctctgtcaag 180

cccacggact caccccagat caagttgtag 210

<210> 246

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 246

gtagcgattg ctagtcatga cggtggcaaa caggctcttg aaaccgtcca acgccttcta 60

ccagttctct gtcaagccca cggactaacc ccagcgcaag ttgtagcgat tgctagtaat 120

attggtggca aacaggctct tgagacggtt cagcgcctcc ttccagttct ctgtcaagcc 180

cacggactca ccccagatca agttgtagca a 211

<210> 247

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 247

gcaattgcta gtcatgacgg tggcaaacag gctcttgaaa ccgtccaacg ccttctacca 60

gttctctgtc aagcccacgg actaacccca gcgcaagttg tagcgattgc tagtaatatt 120

ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg tcaagcccac 180

ggactcaccc cagatcaagt tgtagcgatt 210

<210> 248

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 248

gattgctagt catgacggtg gcaaacaggc tcttgaaacc gtccaacgcc ttctaccagt 60

tctctgtcaa gcccacggac taaccccagc gcaagttgta gcgattgcta gtaatattgg 120

tggcaaacag gctcttgaga cggttcagcg cctccttcca gttctctgtc aagcccacgg 180

actcacccca gatcaagttg tagcgatagc c 211

<210> 249

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 249

agccagtcat gacggtggca aacaggctct tgaaaccgtc caacgccttc taccagttct 60

ctgtcaagcc cacggactaa ccccagcgca agttgtagcg attgctagta atattggtgg 120

caaacaggct cttgagacgg ttcagcgcct ccttccagtt ctctgtcaag cccacggact 180

caccccagat caagttgtag cgattgcaag t 211

<210> 250

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 250

aagtcatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60

tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtaata ttggtggcaa 120

acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180

cccagatcaa gttgtagcga ttgcttcc 208

<210> 251

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 251

ttcccatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60

tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtaata ttggtggcaa 120

acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180

cccagatcaa gttgtagcga ttgcctct 208

<210> 252

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 252

ctctcatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60

tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtaata ttggtggcaa 120

acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180

cccagatcaa gttgtagcga ttgcgtca 208

<210> 253

<211> 216

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 253

ccccggagca ggtggtggcc atcgctagtc atgacggtgg caaacaggct cttgaaaccg 60

tccaacgcct tctaccagtt ctctgtcaag cccacggact aaccccagcg caagttgtag 120

cgattgctag tcatgacggt ggcaaacagg ctcttgaaac cgtccaacgc cttctaccag 180

ttctctgtca agcccacgga ctaaccccag cgcagg 216

<210> 254

<211> 212

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 254

caggttgtag cgattgctag tcatgacggt ggcaaacagg ctcttgaaac cgtccaacgc 60

cttctaccag ttctctgtca agcccacgga ctaaccccag cgcaagttgt agcgattgct 120

agtcatgacg gtggcaaaca ggctcttgaa accgtccaac gccttctacc agttctctgt 180

caagcccacg gactaacccc agcgcaagtg gt 212

<210> 255

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 255

tggtagcgat tgctagtcat gacggtggca aacaggctct tgaaaccgtc caacgccttc 60

taccagttct ctgtcaagcc cacggactaa ccccagcgca agttgtagcg attgctagtc 120

atgacggtgg caaacaggct cttgaaaccg tccaacgcct tctaccagtt ctctgtcaag 180

cccacggact aaccccagcg caagttgtag 210

<210> 256

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 256

gtagcgattg ctagtcatga cggtggcaaa caggctcttg aaaccgtcca acgccttcta 60

ccagttctct gtcaagccca cggactaacc ccagcgcaag ttgtagcgat tgctagtcat 120

gacggtggca aacaggctct tgaaaccgtc caacgccttc taccagttct ctgtcaagcc 180

cacggactaa ccccagcgca agttgtagca a 211

<210> 257

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 257

gcaattgcta gtcatgacgg tggcaaacag gctcttgaaa ccgtccaacg ccttctacca 60

gttctctgtc aagcccacgg actaacccca gcgcaagttg tagcgattgc tagtcatgac 120

ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg tcaagcccac 180

ggactaaccc cagcgcaagt tgtagcgatt 210

<210> 258

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 258

gattgctagt catgacggtg gcaaacaggc tcttgaaacc gtccaacgcc ttctaccagt 60

tctctgtcaa gcccacggac taaccccagc gcaagttgta gcgattgcta gtcatgacgg 120

tggcaaacag gctcttgaaa ccgtccaacg ccttctacca gttctctgtc aagcccacgg 180

actaacccca gcgcaagttg tagcgatagc c 211

<210> 259

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 259

agccagtcat gacggtggca aacaggctct tgaaaccgtc caacgccttc taccagttct 60

ctgtcaagcc cacggactaa ccccagcgca agttgtagcg attgctagtc atgacggtgg 120

caaacaggct cttgaaaccg tccaacgcct tctaccagtt ctctgtcaag cccacggact 180

aaccccagcg caagttgtag cgattgcaag t 211

<210> 260

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 260

aagtcatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60

tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtcatg acggtggcaa 120

acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180

cccagcgcaa gttgtagcga ttgcttcc 208

<210> 261

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 261

ttcccatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60

tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtcatg acggtggcaa 120

acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180

cccagcgcaa gttgtagcga ttgcctct 208

<210> 262

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 262

ctctcatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60

tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtcatg acggtggcaa 120

acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180

cccagcgcaa gttgtagcga ttgcgtca 208

<210> 263

<211> 216

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 263

ccccggagca ggtggtggcc atcgctagtc atgacggtgg caaacaggct cttgaaaccg 60

tccaacgcct tctaccagtt ctctgtcaag cccacggact aaccccagcg caagttgtag 120

cgattgctag taacaatggt ggcaaacagg ctcttgaaac cgtacagcgc ctactgccag 180

ttctctgtca agcccacggt ctgactccgg agcagg 216

<210> 264

<211> 212

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 264

caggttgtag cgattgctag tcatgacggt ggcaaacagg ctcttgaaac cgtccaacgc 60

cttctaccag ttctctgtca agcccacgga ctaaccccag cgcaagttgt agcgattgct 120

agtaacaatg gtggcaaaca ggctcttgaa accgtacagc gcctactgcc agttctctgt 180

caagcccacg gtctgactcc ggagcaagtg gt 212

<210> 265

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 265

tggtagcgat tgctagtcat gacggtggca aacaggctct tgaaaccgtc caacgccttc 60

taccagttct ctgtcaagcc cacggactaa ccccagcgca agttgtagcg attgctagta 120

acaatggtgg caaacaggct cttgaaaccg tacagcgcct actgccagtt ctctgtcaag 180

cccacggtct gactccggag caagttgtag 210

<210> 266

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 266

gtagcgattg ctagtcatga cggtggcaaa caggctcttg aaaccgtcca acgccttcta 60

ccagttctct gtcaagccca cggactaacc ccagcgcaag ttgtagcgat tgctagtaac 120

aatggtggca aacaggctct tgaaaccgta cagcgcctac tgccagttct ctgtcaagcc 180

cacggtctga ctccggagca agttgtagca a 211

<210> 267

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 267

gcaattgcta gtcatgacgg tggcaaacag gctcttgaaa ccgtccaacg ccttctacca 60

gttctctgtc aagcccacgg actaacccca gcgcaagttg tagcgattgc tagtaacaat 120

ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg tcaagcccac 180

ggtctgactc cggagcaagt tgtagcgatt 210

<210> 268

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 268

gattgctagt catgacggtg gcaaacaggc tcttgaaacc gtccaacgcc ttctaccagt 60

tctctgtcaa gcccacggac taaccccagc gcaagttgta gcgattgcta gtaacaatgg 120

tggcaaacag gctcttgaaa ccgtacagcg cctactgcca gttctctgtc aagcccacgg 180

tctgactccg gagcaagttg tagcgatagc c 211

<210> 269

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 269

agccagtcat gacggtggca aacaggctct tgaaaccgtc caacgccttc taccagttct 60

ctgtcaagcc cacggactaa ccccagcgca agttgtagcg attgctagta acaatggtgg 120

caaacaggct cttgaaaccg tacagcgcct actgccagtt ctctgtcaag cccacggtct 180

gactccggag caagttgtag cgattgcaag t 211

<210> 270

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 270

aagtcatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60

tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtaaca atggtggcaa 120

acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180

tccggagcaa gttgtagcga ttgcttcc 208

<210> 271

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 271

ttcccatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60

tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtaaca atggtggcaa 120

acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180

tccggagcaa gttgtagcga ttgcctct 208

<210> 272

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 272

ctctcatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60

tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtaaca atggtggcaa 120

acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180

tccggagcaa gttgtagcga ttgcgtca 208

<210> 273

<211> 216

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 273

ccccggagca ggtggtggcc atcgctagtc atgacggtgg caaacaggct cttgaaaccg 60

tccaacgcct tctaccagtt ctctgtcaag cccacggact aaccccagcg caagttgtag 120

cgattgctag taatgggggt ggcaaacagg ctcttgagac tgttcagcgc cttctaccag 180

ttctctgtca agcccacggc ctgacgcccg agcagg 216

<210> 274

<211> 212

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 274

caggttgtag cgattgctag tcatgacggt ggcaaacagg ctcttgaaac cgtccaacgc 60

cttctaccag ttctctgtca agcccacgga ctaaccccag cgcaagttgt agcgattgct 120

agtaatgggg gtggcaaaca ggctcttgag actgttcagc gccttctacc agttctctgt 180

caagcccacg gcctgacgcc cgagcaagtg gt 212

<210> 275

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 275

tggtagcgat tgctagtcat gacggtggca aacaggctct tgaaaccgtc caacgccttc 60

taccagttct ctgtcaagcc cacggactaa ccccagcgca agttgtagcg attgctagta 120

atgggggtgg caaacaggct cttgagactg ttcagcgcct tctaccagtt ctctgtcaag 180

cccacggcct gacgcccgag caagttgtag 210

<210> 276

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 276

gtagcgattg ctagtcatga cggtggcaaa caggctcttg aaaccgtcca acgccttcta 60

ccagttctct gtcaagccca cggactaacc ccagcgcaag ttgtagcgat tgctagtaat 120

gggggtggca aacaggctct tgagactgtt cagcgccttc taccagttct ctgtcaagcc 180

cacggcctga cgcccgagca agttgtagca a 211

<210> 277

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 277

gcaattgcta gtcatgacgg tggcaaacag gctcttgaaa ccgtccaacg ccttctacca 60

gttctctgtc aagcccacgg actaacccca gcgcaagttg tagcgattgc tagtaatggg 120

ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg tcaagcccac 180

ggcctgacgc ccgagcaagt tgtagcgatt 210

<210> 278

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 278

gattgctagt catgacggtg gcaaacaggc tcttgaaacc gtccaacgcc ttctaccagt 60

tctctgtcaa gcccacggac taaccccagc gcaagttgta gcgattgcta gtaatggggg 120

tggcaaacag gctcttgaga ctgttcagcg ccttctacca gttctctgtc aagcccacgg 180

cctgacgccc gagcaagttg tagcgatagc c 211

<210> 279

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 279

agccagtcat gacggtggca aacaggctct tgaaaccgtc caacgccttc taccagttct 60

ctgtcaagcc cacggactaa ccccagcgca agttgtagcg attgctagta atgggggtgg 120

caaacaggct cttgagactg ttcagcgcct tctaccagtt ctctgtcaag cccacggcct 180

gacgcccgag caagttgtag cgattgcaag t 211

<210> 280

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 280

aagtcatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60

tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtaatg ggggtggcaa 120

acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180

gcccgagcaa gttgtagcga ttgcttcc 208

<210> 281

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 281

ttcccatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60

tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtaatg ggggtggcaa 120

acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180

gcccgagcaa gttgtagcga ttgcctct 208

<210> 282

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 282

ctctcatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60

tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gctagtaatg ggggtggcaa 120

acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180

gcccgagcaa gttgtagcga ttgcgtca 208

<210> 283

<211> 216

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 283

ccccggagca ggtggtggcc atcgctagta acaatggtgg caaacaggct cttgaaaccg 60

tacagcgcct actgccagtt ctctgtcaag cccacggtct gactccggag caagttgtag 120

cgattgctag taatattggt ggcaaacagg ctcttgagac ggttcagcgc ctccttccag 180

ttctctgtca agcccacgga ctcaccccag atcagg 216

<210> 284

<211> 212

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 284

caggttgtag cgattgctag taacaatggt ggcaaacagg ctcttgaaac cgtacagcgc 60

ctactgccag ttctctgtca agcccacggt ctgactccgg agcaagttgt agcgattgct 120

agtaatattg gtggcaaaca ggctcttgag acggttcagc gcctccttcc agttctctgt 180

caagcccacg gactcacccc agatcaagtg gt 212

<210> 285

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 285

tggtagcgat tgctagtaac aatggtggca aacaggctct tgaaaccgta cagcgcctac 60

tgccagttct ctgtcaagcc cacggtctga ctccggagca agttgtagcg attgctagta 120

atattggtgg caaacaggct cttgagacgg ttcagcgcct ccttccagtt ctctgtcaag 180

cccacggact caccccagat caagttgtag 210

<210> 286

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 286

gtagcgattg ctagtaacaa tggtggcaaa caggctcttg aaaccgtaca gcgcctactg 60

ccagttctct gtcaagccca cggtctgact ccggagcaag ttgtagcgat tgctagtaat 120

attggtggca aacaggctct tgagacggtt cagcgcctcc ttccagttct ctgtcaagcc 180

cacggactca ccccagatca agttgtagca a 211

<210> 287

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 287

gcaattgcta gtaacaatgg tggcaaacag gctcttgaaa ccgtacagcg cctactgcca 60

gttctctgtc aagcccacgg tctgactccg gagcaagttg tagcgattgc tagtaatatt 120

ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg tcaagcccac 180

ggactcaccc cagatcaagt tgtagcgatt 210

<210> 288

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 288

gattgctagt aacaatggtg gcaaacaggc tcttgaaacc gtacagcgcc tactgccagt 60

tctctgtcaa gcccacggtc tgactccgga gcaagttgta gcgattgcta gtaatattgg 120

tggcaaacag gctcttgaga cggttcagcg cctccttcca gttctctgtc aagcccacgg 180

actcacccca gatcaagttg tagcgatagc c 211

<210> 289

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 289

agccagtaac aatggtggca aacaggctct tgaaaccgta cagcgcctac tgccagttct 60

ctgtcaagcc cacggtctga ctccggagca agttgtagcg attgctagta atattggtgg 120

caaacaggct cttgagacgg ttcagcgcct ccttccagtt ctctgtcaag cccacggact 180

caccccagat caagttgtag cgattgcaag t 211

<210> 290

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 290

aagtaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60

tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtaata ttggtggcaa 120

acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180

cccagatcaa gttgtagcga ttgcttcc 208

<210> 291

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 291

ttccaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60

tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtaata ttggtggcaa 120

acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180

cccagatcaa gttgtagcga ttgcctct 208

<210> 292

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 292

ctctaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60

tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtaata ttggtggcaa 120

acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180

cccagatcaa gttgtagcga ttgcgtca 208

<210> 293

<211> 216

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 293

ccccggagca ggtggtggcc atcgctagta acaatggtgg caaacaggct cttgaaaccg 60

tacagcgcct actgccagtt ctctgtcaag cccacggtct gactccggag caagttgtag 120

cgattgctag tcatgacggt ggcaaacagg ctcttgaaac cgtccaacgc cttctaccag 180

ttctctgtca agcccacgga ctaaccccag cgcagg 216

<210> 294

<211> 212

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 294

caggttgtag cgattgctag taacaatggt ggcaaacagg ctcttgaaac cgtacagcgc 60

ctactgccag ttctctgtca agcccacggt ctgactccgg agcaagttgt agcgattgct 120

agtcatgacg gtggcaaaca ggctcttgaa accgtccaac gccttctacc agttctctgt 180

caagcccacg gactaacccc agcgcaagtg gt 212

<210> 295

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 295

tggtagcgat tgctagtaac aatggtggca aacaggctct tgaaaccgta cagcgcctac 60

tgccagttct ctgtcaagcc cacggtctga ctccggagca agttgtagcg attgctagtc 120

atgacggtgg caaacaggct cttgaaaccg tccaacgcct tctaccagtt ctctgtcaag 180

cccacggact aaccccagcg caagttgtag 210

<210> 296

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 296

gtagcgattg ctagtaacaa tggtggcaaa caggctcttg aaaccgtaca gcgcctactg 60

ccagttctct gtcaagccca cggtctgact ccggagcaag ttgtagcgat tgctagtcat 120

gacggtggca aacaggctct tgaaaccgtc caacgccttc taccagttct ctgtcaagcc 180

cacggactaa ccccagcgca agttgtagca a 211

<210> 297

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 297

gcaattgcta gtaacaatgg tggcaaacag gctcttgaaa ccgtacagcg cctactgcca 60

gttctctgtc aagcccacgg tctgactccg gagcaagttg tagcgattgc tagtcatgac 120

ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg tcaagcccac 180

ggactaaccc cagcgcaagt tgtagcgatt 210

<210> 298

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 298

gattgctagt aacaatggtg gcaaacaggc tcttgaaacc gtacagcgcc tactgccagt 60

tctctgtcaa gcccacggtc tgactccgga gcaagttgta gcgattgcta gtcatgacgg 120

tggcaaacag gctcttgaaa ccgtccaacg ccttctacca gttctctgtc aagcccacgg 180

actaacccca gcgcaagttg tagcgatagc c 211

<210> 299

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 299

agccagtaac aatggtggca aacaggctct tgaaaccgta cagcgcctac tgccagttct 60

ctgtcaagcc cacggtctga ctccggagca agttgtagcg attgctagtc atgacggtgg 120

caaacaggct cttgaaaccg tccaacgcct tctaccagtt ctctgtcaag cccacggact 180

aaccccagcg caagttgtag cgattgcaag t 211

<210> 300

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 300

aagtaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60

tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtcatg acggtggcaa 120

acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180

cccagcgcaa gttgtagcga ttgcttcc 208

<210> 301

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 301

ttccaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60

tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtcatg acggtggcaa 120

acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180

cccagcgcaa gttgtagcga ttgcctct 208

<210> 302

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 302

ctctaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60

tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtcatg acggtggcaa 120

acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180

cccagcgcaa gttgtagcga ttgcgtca 208

<210> 303

<211> 216

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 303

ccccggagca ggtggtggcc atcgctagta acaatggtgg caaacaggct cttgaaaccg 60

tacagcgcct actgccagtt ctctgtcaag cccacggtct gactccggag caagttgtag 120

cgattgctag taacaatggt ggcaaacagg ctcttgaaac cgtacagcgc ctactgccag 180

ttctctgtca agcccacggt ctgactccgg agcagg 216

<210> 304

<211> 212

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 304

caggttgtag cgattgctag taacaatggt ggcaaacagg ctcttgaaac cgtacagcgc 60

ctactgccag ttctctgtca agcccacggt ctgactccgg agcaagttgt agcgattgct 120

agtaacaatg gtggcaaaca ggctcttgaa accgtacagc gcctactgcc agttctctgt 180

caagcccacg gtctgactcc ggagcaagtg gt 212

<210> 305

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 305

tggtagcgat tgctagtaac aatggtggca aacaggctct tgaaaccgta cagcgcctac 60

tgccagttct ctgtcaagcc cacggtctga ctccggagca agttgtagcg attgctagta 120

acaatggtgg caaacaggct cttgaaaccg tacagcgcct actgccagtt ctctgtcaag 180

cccacggtct gactccggag caagttgtag 210

<210> 306

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 306

gtagcgattg ctagtaacaa tggtggcaaa caggctcttg aaaccgtaca gcgcctactg 60

ccagttctct gtcaagccca cggtctgact ccggagcaag ttgtagcgat tgctagtaac 120

aatggtggca aacaggctct tgaaaccgta cagcgcctac tgccagttct ctgtcaagcc 180

cacggtctga ctccggagca agttgtagca a 211

<210> 307

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 307

gcaattgcta gtaacaatgg tggcaaacag gctcttgaaa ccgtacagcg cctactgcca 60

gttctctgtc aagcccacgg tctgactccg gagcaagttg tagcgattgc tagtaacaat 120

ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg tcaagcccac 180

ggtctgactc cggagcaagt tgtagcgatt 210

<210> 308

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 308

gattgctagt aacaatggtg gcaaacaggc tcttgaaacc gtacagcgcc tactgccagt 60

tctctgtcaa gcccacggtc tgactccgga gcaagttgta gcgattgcta gtaacaatgg 120

tggcaaacag gctcttgaaa ccgtacagcg cctactgcca gttctctgtc aagcccacgg 180

tctgactccg gagcaagttg tagcgatagc c 211

<210> 309

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 309

agccagtaac aatggtggca aacaggctct tgaaaccgta cagcgcctac tgccagttct 60

ctgtcaagcc cacggtctga ctccggagca agttgtagcg attgctagta acaatggtgg 120

caaacaggct cttgaaaccg tacagcgcct actgccagtt ctctgtcaag cccacggtct 180

gactccggag caagttgtag cgattgcaag t 211

<210> 310

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 310

aagtaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60

tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtaaca atggtggcaa 120

acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180

tccggagcaa gttgtagcga ttgcttcc 208

<210> 311

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 311

ttccaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60

tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtaaca atggtggcaa 120

acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180

tccggagcaa gttgtagcga ttgcctct 208

<210> 312

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 312

ctctaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60

tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtaaca atggtggcaa 120

acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180

tccggagcaa gttgtagcga ttgcgtca 208

<210> 313

<211> 216

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 313

ccccggagca ggtggtggcc atcgctagta acaatggtgg caaacaggct cttgaaaccg 60

tacagcgcct actgccagtt ctctgtcaag cccacggtct gactccggag caagttgtag 120

cgattgctag taatgggggt ggcaaacagg ctcttgagac tgttcagcgc cttctaccag 180

ttctctgtca agcccacggc ctgacgcccg agcagg 216

<210> 314

<211> 212

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 314

caggttgtag cgattgctag taacaatggt ggcaaacagg ctcttgaaac cgtacagcgc 60

ctactgccag ttctctgtca agcccacggt ctgactccgg agcaagttgt agcgattgct 120

agtaatgggg gtggcaaaca ggctcttgag actgttcagc gccttctacc agttctctgt 180

caagcccacg gcctgacgcc cgagcaagtg gt 212

<210> 315

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 315

tggtagcgat tgctagtaac aatggtggca aacaggctct tgaaaccgta cagcgcctac 60

tgccagttct ctgtcaagcc cacggtctga ctccggagca agttgtagcg attgctagta 120

atgggggtgg caaacaggct cttgagactg ttcagcgcct tctaccagtt ctctgtcaag 180

cccacggcct gacgcccgag caagttgtag 210

<210> 316

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 316

gtagcgattg ctagtaacaa tggtggcaaa caggctcttg aaaccgtaca gcgcctactg 60

ccagttctct gtcaagccca cggtctgact ccggagcaag ttgtagcgat tgctagtaat 120

gggggtggca aacaggctct tgagactgtt cagcgccttc taccagttct ctgtcaagcc 180

cacggcctga cgcccgagca agttgtagca a 211

<210> 317

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 317

gcaattgcta gtaacaatgg tggcaaacag gctcttgaaa ccgtacagcg cctactgcca 60

gttctctgtc aagcccacgg tctgactccg gagcaagttg tagcgattgc tagtaatggg 120

ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg tcaagcccac 180

ggcctgacgc ccgagcaagt tgtagcgatt 210

<210> 318

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 318

gattgctagt aacaatggtg gcaaacaggc tcttgaaacc gtacagcgcc tactgccagt 60

tctctgtcaa gcccacggtc tgactccgga gcaagttgta gcgattgcta gtaatggggg 120

tggcaaacag gctcttgaga ctgttcagcg ccttctacca gttctctgtc aagcccacgg 180

cctgacgccc gagcaagttg tagcgatagc c 211

<210> 319

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 319

agccagtaac aatggtggca aacaggctct tgaaaccgta cagcgcctac tgccagttct 60

ctgtcaagcc cacggtctga ctccggagca agttgtagcg attgctagta atgggggtgg 120

caaacaggct cttgagactg ttcagcgcct tctaccagtt ctctgtcaag cccacggcct 180

gacgcccgag caagttgtag cgattgcaag t 211

<210> 320

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 320

aagtaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60

tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtaatg ggggtggcaa 120

acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180

gcccgagcaa gttgtagcga ttgcttcc 208

<210> 321

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 321

ttccaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60

tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtaatg ggggtggcaa 120

acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180

gcccgagcaa gttgtagcga ttgcctct 208

<210> 322

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 322

ctctaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60

tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gctagtaatg ggggtggcaa 120

acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180

gcccgagcaa gttgtagcga ttgcgtca 208

<210> 323

<211> 216

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 323

ccccggagca ggtggtggcc atcgctagta atgggggtgg caaacaggct cttgagactg 60

ttcagcgcct tctaccagtt ctctgtcaag cccacggcct gacgcccgag caagttgtag 120

cgattgctag taatattggt ggcaaacagg ctcttgagac ggttcagcgc ctccttccag 180

ttctctgtca agcccacgga ctcaccccag atcagg 216

<210> 324

<211> 212

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 324

caggttgtag cgattgctag taatgggggt ggcaaacagg ctcttgagac tgttcagcgc 60

cttctaccag ttctctgtca agcccacggc ctgacgcccg agcaagttgt agcgattgct 120

agtaatattg gtggcaaaca ggctcttgag acggttcagc gcctccttcc agttctctgt 180

caagcccacg gactcacccc agatcaagtg gt 212

<210> 325

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 325

tggtagcgat tgctagtaat gggggtggca aacaggctct tgagactgtt cagcgccttc 60

taccagttct ctgtcaagcc cacggcctga cgcccgagca agttgtagcg attgctagta 120

atattggtgg caaacaggct cttgagacgg ttcagcgcct ccttccagtt ctctgtcaag 180

cccacggact caccccagat caagttgtag 210

<210> 326

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 326

gtagcgattg ctagtaatgg gggtggcaaa caggctcttg agactgttca gcgccttcta 60

ccagttctct gtcaagccca cggcctgacg cccgagcaag ttgtagcgat tgctagtaat 120

attggtggca aacaggctct tgagacggtt cagcgcctcc ttccagttct ctgtcaagcc 180

cacggactca ccccagatca agttgtagca a 211

<210> 327

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 327

gcaattgcta gtaatggggg tggcaaacag gctcttgaga ctgttcagcg ccttctacca 60

gttctctgtc aagcccacgg cctgacgccc gagcaagttg tagcgattgc tagtaatatt 120

ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg tcaagcccac 180

ggactcaccc cagatcaagt tgtagcgatt 210

<210> 328

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 328

gattgctagt aatgggggtg gcaaacaggc tcttgagact gttcagcgcc ttctaccagt 60

tctctgtcaa gcccacggcc tgacgcccga gcaagttgta gcgattgcta gtaatattgg 120

tggcaaacag gctcttgaga cggttcagcg cctccttcca gttctctgtc aagcccacgg 180

actcacccca gatcaagttg tagcgatagc c 211

<210> 329

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 329

agccagtaat gggggtggca aacaggctct tgagactgtt cagcgccttc taccagttct 60

ctgtcaagcc cacggcctga cgcccgagca agttgtagcg attgctagta atattggtgg 120

caaacaggct cttgagacgg ttcagcgcct ccttccagtt ctctgtcaag cccacggact 180

caccccagat caagttgtag cgattgcaag t 211

<210> 330

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 330

aagtaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60

tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtaata ttggtggcaa 120

acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180

cccagatcaa gttgtagcga ttgcttcc 208

<210> 331

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 331

ttccaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60

tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtaata ttggtggcaa 120

acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180

cccagatcaa gttgtagcga ttgcctct 208

<210> 332

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 332

ctctaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60

tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtaata ttggtggcaa 120

acaggctctt gagacggttc agcgcctcct tccagttctc tgtcaagccc acggactcac 180

cccagatcaa gttgtagcga ttgcgtca 208

<210> 333

<211> 216

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 333

ccccggagca ggtggtggcc atcgctagta atgggggtgg caaacaggct cttgagactg 60

ttcagcgcct tctaccagtt ctctgtcaag cccacggcct gacgcccgag caagttgtag 120

cgattgctag tcatgacggt ggcaaacagg ctcttgaaac cgtccaacgc cttctaccag 180

ttctctgtca agcccacgga ctaaccccag cgcagg 216

<210> 334

<211> 212

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 334

caggttgtag cgattgctag taatgggggt ggcaaacagg ctcttgagac tgttcagcgc 60

cttctaccag ttctctgtca agcccacggc ctgacgcccg agcaagttgt agcgattgct 120

agtcatgacg gtggcaaaca ggctcttgaa accgtccaac gccttctacc agttctctgt 180

caagcccacg gactaacccc agcgcaagtg gt 212

<210> 335

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 335

tggtagcgat tgctagtaat gggggtggca aacaggctct tgagactgtt cagcgccttc 60

taccagttct ctgtcaagcc cacggcctga cgcccgagca agttgtagcg attgctagtc 120

atgacggtgg caaacaggct cttgaaaccg tccaacgcct tctaccagtt ctctgtcaag 180

cccacggact aaccccagcg caagttgtag 210

<210> 336

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 336

gtagcgattg ctagtaatgg gggtggcaaa caggctcttg agactgttca gcgccttcta 60

ccagttctct gtcaagccca cggcctgacg cccgagcaag ttgtagcgat tgctagtcat 120

gacggtggca aacaggctct tgaaaccgtc caacgccttc taccagttct ctgtcaagcc 180

cacggactaa ccccagcgca agttgtagca a 211

<210> 337

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 337

gcaattgcta gtaatggggg tggcaaacag gctcttgaga ctgttcagcg ccttctacca 60

gttctctgtc aagcccacgg cctgacgccc gagcaagttg tagcgattgc tagtcatgac 120

ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg tcaagcccac 180

ggactaaccc cagcgcaagt tgtagcgatt 210

<210> 338

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 338

gattgctagt aatgggggtg gcaaacaggc tcttgagact gttcagcgcc ttctaccagt 60

tctctgtcaa gcccacggcc tgacgcccga gcaagttgta gcgattgcta gtcatgacgg 120

tggcaaacag gctcttgaaa ccgtccaacg ccttctacca gttctctgtc aagcccacgg 180

actaacccca gcgcaagttg tagcgatagc c 211

<210> 339

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 339

agccagtaat gggggtggca aacaggctct tgagactgtt cagcgccttc taccagttct 60

ctgtcaagcc cacggcctga cgcccgagca agttgtagcg attgctagtc atgacggtgg 120

caaacaggct cttgaaaccg tccaacgcct tctaccagtt ctctgtcaag cccacggact 180

aaccccagcg caagttgtag cgattgcaag t 211

<210> 340

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 340

aagtaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60

tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtcatg acggtggcaa 120

acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180

cccagcgcaa gttgtagcga ttgcttcc 208

<210> 341

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 341

ttccaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60

tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtcatg acggtggcaa 120

acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180

cccagcgcaa gttgtagcga ttgcctct 208

<210> 342

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 342

ctctaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60

tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtcatg acggtggcaa 120

acaggctctt gaaaccgtcc aacgccttct accagttctc tgtcaagccc acggactaac 180

cccagcgcaa gttgtagcga ttgcgtca 208

<210> 343

<211> 216

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 343

ccccggagca ggtggtggcc atcgctagta atgggggtgg caaacaggct cttgagactg 60

ttcagcgcct tctaccagtt ctctgtcaag cccacggcct gacgcccgag caagttgtag 120

cgattgctag taacaatggt ggcaaacagg ctcttgaaac cgtacagcgc ctactgccag 180

ttctctgtca agcccacggt ctgactccgg agcagg 216

<210> 344

<211> 212

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 344

caggttgtag cgattgctag taatgggggt ggcaaacagg ctcttgagac tgttcagcgc 60

cttctaccag ttctctgtca agcccacggc ctgacgcccg agcaagttgt agcgattgct 120

agtaacaatg gtggcaaaca ggctcttgaa accgtacagc gcctactgcc agttctctgt 180

caagcccacg gtctgactcc ggagcaagtg gt 212

<210> 345

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 345

tggtagcgat tgctagtaat gggggtggca aacaggctct tgagactgtt cagcgccttc 60

taccagttct ctgtcaagcc cacggcctga cgcccgagca agttgtagcg attgctagta 120

acaatggtgg caaacaggct cttgaaaccg tacagcgcct actgccagtt ctctgtcaag 180

cccacggtct gactccggag caagttgtag 210

<210> 346

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 346

gtagcgattg ctagtaatgg gggtggcaaa caggctcttg agactgttca gcgccttcta 60

ccagttctct gtcaagccca cggcctgacg cccgagcaag ttgtagcgat tgctagtaac 120

aatggtggca aacaggctct tgaaaccgta cagcgcctac tgccagttct ctgtcaagcc 180

cacggtctga ctccggagca agttgtagca a 211

<210> 347

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 347

gcaattgcta gtaatggggg tggcaaacag gctcttgaga ctgttcagcg ccttctacca 60

gttctctgtc aagcccacgg cctgacgccc gagcaagttg tagcgattgc tagtaacaat 120

ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg tcaagcccac 180

ggtctgactc cggagcaagt tgtagcgatt 210

<210> 348

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 348

gattgctagt aatgggggtg gcaaacaggc tcttgagact gttcagcgcc ttctaccagt 60

tctctgtcaa gcccacggcc tgacgcccga gcaagttgta gcgattgcta gtaacaatgg 120

tggcaaacag gctcttgaaa ccgtacagcg cctactgcca gttctctgtc aagcccacgg 180

tctgactccg gagcaagttg tagcgatagc c 211

<210> 349

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 349

agccagtaat gggggtggca aacaggctct tgagactgtt cagcgccttc taccagttct 60

ctgtcaagcc cacggcctga cgcccgagca agttgtagcg attgctagta acaatggtgg 120

caaacaggct cttgaaaccg tacagcgcct actgccagtt ctctgtcaag cccacggtct 180

gactccggag caagttgtag cgattgcaag t 211

<210> 350

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 350

aagtaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60

tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtaaca atggtggcaa 120

acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180

tccggagcaa gttgtagcga ttgcttcc 208

<210> 351

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 351

ttccaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60

tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtaaca atggtggcaa 120

acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180

tccggagcaa gttgtagcga ttgcctct 208

<210> 352

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 352

ctctaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60

tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtaaca atggtggcaa 120

acaggctctt gaaaccgtac agcgcctact gccagttctc tgtcaagccc acggtctgac 180

tccggagcaa gttgtagcga ttgcgtca 208

<210> 353

<211> 216

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 353

ccccggagca ggtggtggcc atcgctagta atgggggtgg caaacaggct cttgagactg 60

ttcagcgcct tctaccagtt ctctgtcaag cccacggcct gacgcccgag caagttgtag 120

cgattgctag taatgggggt ggcaaacagg ctcttgagac tgttcagcgc cttctaccag 180

ttctctgtca agcccacggc ctgacgcccg agcagg 216

<210> 354

<211> 212

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 354

caggttgtag cgattgctag taatgggggt ggcaaacagg ctcttgagac tgttcagcgc 60

cttctaccag ttctctgtca agcccacggc ctgacgcccg agcaagttgt agcgattgct 120

agtaatgggg gtggcaaaca ggctcttgag actgttcagc gccttctacc agttctctgt 180

caagcccacg gcctgacgcc cgagcaagtg gt 212

<210> 355

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 355

tggtagcgat tgctagtaat gggggtggca aacaggctct tgagactgtt cagcgccttc 60

taccagttct ctgtcaagcc cacggcctga cgcccgagca agttgtagcg attgctagta 120

atgggggtgg caaacaggct cttgagactg ttcagcgcct tctaccagtt ctctgtcaag 180

cccacggcct gacgcccgag caagttgtag 210

<210> 356

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 356

gtagcgattg ctagtaatgg gggtggcaaa caggctcttg agactgttca gcgccttcta 60

ccagttctct gtcaagccca cggcctgacg cccgagcaag ttgtagcgat tgctagtaat 120

gggggtggca aacaggctct tgagactgtt cagcgccttc taccagttct ctgtcaagcc 180

cacggcctga cgcccgagca agttgtagca a 211

<210> 357

<211> 210

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 357

gcaattgcta gtaatggggg tggcaaacag gctcttgaga ctgttcagcg ccttctacca 60

gttctctgtc aagcccacgg cctgacgccc gagcaagttg tagcgattgc tagtaatggg 120

ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg tcaagcccac 180

ggcctgacgc ccgagcaagt tgtagcgatt 210

<210> 358

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 358

gattgctagt aatgggggtg gcaaacaggc tcttgagact gttcagcgcc ttctaccagt 60

tctctgtcaa gcccacggcc tgacgcccga gcaagttgta gcgattgcta gtaatggggg 120

tggcaaacag gctcttgaga ctgttcagcg ccttctacca gttctctgtc aagcccacgg 180

cctgacgccc gagcaagttg tagcgatagc c 211

<210> 359

<211> 211

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 359

agccagtaat gggggtggca aacaggctct tgagactgtt cagcgccttc taccagttct 60

ctgtcaagcc cacggcctga cgcccgagca agttgtagcg attgctagta atgggggtgg 120

caaacaggct cttgagactg ttcagcgcct tctaccagtt ctctgtcaag cccacggcct 180

gacgcccgag caagttgtag cgattgcaag t 211

<210> 360

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 360

aagtaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60

tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtaatg ggggtggcaa 120

acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180

gcccgagcaa gttgtagcga ttgcttcc 208

<210> 361

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 361

ttccaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60

tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtaatg ggggtggcaa 120

acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180

gcccgagcaa gttgtagcga ttgcctct 208

<210> 362

<211> 208

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 362

ctctaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60

tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gctagtaatg ggggtggcaa 120

acaggctctt gagactgttc agcgccttct accagttctc tgtcaagccc acggcctgac 180

gcccgagcaa gttgtagcga ttgcgtca 208

<210> 363

<211> 109

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 363

agccagtaat attggtggca aacaggctct tgagacggtt cagcgcctcc ttccagttct 60

ctgtcaagcc cacggactca ccccagatca agttgtagcg attgcaagt 109

<210> 364

<211> 106

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 364

aagtaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60

tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gcttcc 106

<210> 365

<211> 106

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 365

ttccaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60

tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gcctct 106

<210> 366

<211> 106

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 366

ctctaatatt ggtggcaaac aggctcttga gacggttcag cgcctccttc cagttctctg 60

tcaagcccac ggactcaccc cagatcaagt tgtagcgatt gcgtca 106

<210> 367

<211> 109

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 367

agccagtcat gacggtggca aacaggctct tgaaaccgtc caacgccttc taccagttct 60

ctgtcaagcc cacggactaa ccccagcgca agttgtagcg attgcaagt 109

<210> 368

<211> 106

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 368

aagtcatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60

tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gcttcc 106

<210> 369

<211> 106

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 369

ttcccatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60

tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gcctct 106

<210> 370

<211> 106

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 370

ctctcatgac ggtggcaaac aggctcttga aaccgtccaa cgccttctac cagttctctg 60

tcaagcccac ggactaaccc cagcgcaagt tgtagcgatt gcgtca 106

<210> 371

<211> 109

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 371

agccagtaac aatggtggca aacaggctct tgaaaccgta cagcgcctac tgccagttct 60

ctgtcaagcc cacggtctga ctccggagca agttgtagcg attgcaagt 109

<210> 372

<211> 106

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 372

aagtaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60

tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gcttcc 106

<210> 373

<211> 106

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 373

ttccaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60

tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gcctct 106

<210> 374

<211> 106

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 374

ctctaacaat ggtggcaaac aggctcttga aaccgtacag cgcctactgc cagttctctg 60

tcaagcccac ggtctgactc cggagcaagt tgtagcgatt gcgtca 106

<210> 375

<211> 109

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 375

agccagtaat gggggtggca aacaggctct tgagactgtt cagcgccttc taccagttct 60

ctgtcaagcc cacggcctga cgcccgagca agttgtagcg attgcaagt 109

<210> 376

<211> 106

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 376

aagtaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60

tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gcttcc 106

<210> 377

<211> 106

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 377

ttccaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60

tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gcctct 106

<210> 378

<211> 106

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 378

ctctaatggg ggtggcaaac aggctcttga gactgttcag cgccttctac cagttctctg 60

tcaagcccac ggcctgacgc ccgagcaagt tgtagcgatt gcgtca 106

<210> 379

<211> 76

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 379

aagtaatatt ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60

tccggcgttg gccgcg 76

<210> 380

<211> 76

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 380

ttccaatatt ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60

tccggcgttg gccgcg 76

<210> 381

<211> 76

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 381

ctctaatatt ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60

tccggcgttg gccgcg 76

<210> 382

<211> 76

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 382

gtcaaatatt ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60

tccggcgttg gccgcg 76

<210> 383

<211> 76

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 383

aagtcatgac ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60

tccggcgttg gccgcg 76

<210> 384

<211> 76

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 384

ttcccatgac ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60

tccggcgttg gccgcg 76

<210> 385

<211> 76

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 385

ctctcatgac ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60

tccggcgttg gccgcg 76

<210> 386

<211> 76

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 386

gtcacatgac ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60

tccggcgttg gccgcg 76

<210> 387

<211> 76

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 387

aagtaacaat ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60

tccggcgttg gccgcg 76

<210> 388

<211> 76

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 388

ttccaacaat ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60

tccggcgttg gccgcg 76

<210> 389

<211> 76

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 389

ctctaacaat ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60

tccggcgttg gccgcg 76

<210> 390

<211> 76

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 390

gtcaaacaat ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60

tccggcgttg gccgcg 76

<210> 391

<211> 76

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 391

aagtaatggg ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60

tccggcgttg gccgcg 76

<210> 392

<211> 76

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 392

ttccaatggg ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60

tccggcgttg gccgcg 76

<210> 393

<211> 76

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 393

ctctaatggg ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60

tccggcgttg gccgcg 76

<210> 394

<211> 76

<212> DNA

<213> Artificial Sequence (Artificial Sequence)

<400> 394

gtcaaatggg ggcggcaggc cggcgctgga gagcattgtt gcccagttat ctcgccctga 60

tccggcgttg gccgcg 76