1. A magnetic drive liquid drop motion testing device comprises a bearing platform; the method is characterized in that: the device also comprises a magnetic field moving assembly, a camera assembly and a liquid drop moving assembly which are arranged on the bearing platform; the liquid drop feeding assembly is positioned at one end of the magnetic field moving assembly; the magnetic field moving assembly comprises a linear module (6), a first three-axis adjusting platform (9), a magnet placing plate (11) and a permanent magnet (12); the first three-axis adjusting platform (9) is arranged on a sliding block of the linear module (6); the magnet placing plate (11) is arranged on the tail end adjusting plate of the first triaxial adjusting platform (9); the magnet placing plate (11) is provided with a permanent magnet (12); the magnet placing plate (11) is made of non-ferromagnetic material;

the liquid drop moving assembly comprises a lifting mechanism (21), a second three-axis adjusting platform (22), a bowl-shaped light source (23) and a liquid drop moving platen (25); the second triaxial adjusting platform (22) is arranged on a lifting plate of the lifting mechanism (21); the bowl-shaped light source (23) and the liquid drop moving platen (25) are both arranged on the tail end adjusting plate of the second three-axis adjusting platform (22); the bowl-shaped light source (23) is positioned right below the liquid drop moving platen (25); the liquid drop moving platen (25) is made of a non-ferromagnetic transparent material;

the camera assembly comprises a camera (13), a first bracket (14), a second bracket (15), an adjusting block (16), a first adjusting bolt (17) and a second adjusting bolt (18); a first bracket (14) which is vertically arranged is fixed on the bearing platform; the adjusting block (16) and the first bracket (14) form a sliding pair or a cylindrical pair which slides along the vertical direction and are locked at different positions through a first adjusting bolt (17); the second bracket (15) and the adjusting block (16) form a sliding pair or a cylindrical pair which slides along the horizontal direction and are locked at different positions through a second adjusting bolt (18); the camera (13) is arranged on the second bracket (15) and is arranged with the head facing downwards; the camera (13) can be moved to a position directly above the droplet moving platen (25).

2. A magnetically actuated droplet motion testing device according to claim 1, wherein: the bearing platform comprises a top plate (2), a middle plate (3), a bottom plate (4) and a profile frame (5); the section bar frame (5) is fixed on the bottom plate (4); the middle plate (3) is fixed in the middle of the section bar frame (5); the top plate (2) is fixed on the top of the section bar frame (5).

3. A magnetically actuated droplet motion testing device according to claim 2, wherein: and a plurality of universal wheels are arranged on the bottom surface of the bottom plate.

4. A magnetically actuated droplet motion testing device according to claim 1, wherein: the permanent magnet (12) adopts an Nd-Fe-B permanent magnet, and the surface magnetic field intensity is 1185 Gs.

5. A magnetically actuated droplet motion testing device according to claim 1, wherein: two photoelectric switches are mounted at two ends of one side of the linear module (6); the photoelectric switch is used for limiting the upper sliding block of the linear module (6).

6. A magnetically actuated droplet motion testing device according to claim 1, wherein: the magnet placing plate (11) is arranged in an elevating manner relative to the first triaxial adjusting platform (9); the droplet moving platen (25) is elevated relative to the second triaxial adjustment stage (22).

7. A magnetically actuated droplet motion testing device according to claim 1, wherein: the lifting mechanism (21) is matched with the guide rail through the fork shearing mechanism to drive the lifting plate at the top to be lifted or lowered; the lifting mechanism (21) is lifted by manual adjustment or motor drive.

8. A magnetically actuated droplet motion testing device according to claim 1, wherein: the top surface of the droplet moving platen (25) is provided with a hydrophobic coating.

9. A magnetically actuated droplet motion testing device according to claim 1, wherein: the magnetic driving liquid drop motion testing device also comprises a liquid drop feeding assembly; the liquid drop feeding assembly comprises a sample injector clamping mechanism (26), a sample pushing mechanism (27), a sample injector height adjusting mechanism (28), an angle adjusting block (29), a fixing plate (31) and an upright post (32); the vertical upright post (32) is fixed on the top plate (2) of the bearing platform; the fixing plate (31) is connected to the upright post (32) through a hoop; the hoop can slide and rotate on the upright post (32); the sample injector height adjusting mechanism (28) is arranged on the fixing plate (31); the sample injector clamping mechanism (26) and the sample pushing and adding mechanism (27) are both arranged on a sliding plate of the sample injector height adjusting mechanism (28); the sample injector clamping mechanism (26) is positioned below the sample injection pushing mechanism (27); the syringe of the injection injector is clamped and fixed on the injector clamping mechanism (26); an injection push rod of the injection sample injector is fixed with a sliding plate on a pushing sample injection mechanism (27); the height adjusting mechanism (28) of the sample injector and the pushing sample injection mechanism (27) adopt electric or manual adjustment sliding tables; the injection port of the injection sample injector is arranged downwards; the injector can be moved to just above the droplet moving platen (25).

10. A method of testing a magnetically actuated droplet motion testing apparatus according to claim 1, wherein: step one, mounting an injection sample injector filled with magnetic liquid on an adjusting liquid drop feeding assembly; adjusting the position of an injection injector on the droplet feed assembly to be directly above the droplet moving platen (25); adjusting the distance from an injection port of the injection injector to the liquid drop moving platen (25) by an injector height adjusting mechanism (28), and dropping a magnetic liquid drop with a preset volume on the liquid drop moving platen (25) by the injection injector by pushing an injector mechanism (27);

step two, moving away an injection sample injector on the liquid drop feeding assembly; adjusting a camera (13) in the camera assembly to be directly above the droplet moving platen (25); adjusting the brightness of the bowl-shaped light source (23) to make the edges of the magnetic liquid drops shot by the camera (13) clear;

thirdly, the lifting mechanism (21) adjusts the height of the magnetic liquid drops; the center position of the magnetic liquid drop is adjusted through a second triaxial adjusting platform (22), so that the central axis of the magnetic field of the permanent magnet (12) passes through the center position of the magnetic liquid drop;

fourthly, adjusting the position of the permanent magnet (12) through a linear module (6) on the sliding table assembly or a first three-axis adjusting platform (9); the camera (13) continuously shoots the magnetic liquid drops in the moving process of the permanent magnet (12) and records the behavior process of the magnetic liquid drops; the user can observe the deformation and movement of the magnetic liquid drop in the magnetic field moving process by using the shot picture.

Background

Droplet operations are fundamental to many applications, such as water collection, medical diagnostics, and drug delivery. Liquid manipulation based on structure has found wide application in both nature and in artificial materials. Controllable manipulation of droplets is a key to a wide range of applications, such as water collection and transport, biological identification, and chemical reactions. Many plants and animals in nature manipulate droplets by taking advantage of their structure. Prototype examples include cactus, spider silk and nano-grade bushy beetles, which collect and move water droplets with conical spines, periodic raised structures and bump structures, respectively. These asymmetric intrinsic structures can cause a difference in laplace pressure gradient in the water droplet, causing the droplet to move in a predetermined direction. Inspired by these droplet operations, various external forces including electricity, magnetism, sound, light, and wetted surfaces are used to drive droplets, where magnetically operating droplets has the advantages of remote actuation, safety, ease of control, and the like. In order to realize the magnetic driving of the liquid drop, the object to be measured is usually combined with the magnetic material, and the external magnetic field is controlled to control the movement of the object to be measured in different control planes, that is, the external magnetic field provides the magnetic material attraction, so that the object to be measured combined with the magnetic material moves according to the attraction provided by the external magnetic field. However, the method of providing magnetic material attraction force by magnetic field to control the movement of magnetic material usually requires expensive equipment and special technical support, and the process is complicated. In addition, in most of the situations of magnetically driving the liquid drop, a complex algorithm needs to be designed in advance for the liquid drop movement operation under a fixed movement track.

Disclosure of Invention

The invention aims to provide a magnetic driving liquid drop motion testing device and a testing method thereof aiming at improving the diversity and flexibility of magnetic driving liquid drop testing.

The invention relates to a magnetic drive liquid drop motion testing device which comprises a bearing platform, a magnetic field moving assembly, a camera assembly and a liquid drop moving assembly, wherein the magnetic field moving assembly, the camera assembly and the liquid drop moving assembly are arranged on the bearing platform. The liquid drop feeding assembly is positioned at one end of the magnetic field moving assembly. The magnetic field moving assembly comprises a linear module, a first three-axis adjusting platform, a magnet placing plate and a permanent magnet. The first three-axis adjusting platform is arranged on a sliding block of the linear module; the magnet placing plate is installed on the tail end adjusting plate of the first triaxial adjusting platform. The magnet placing plate is provided with a permanent magnet. The magnet placing plate is made of non-ferromagnetic material.

The liquid drop moving assembly comprises a lifting mechanism, a second three-axis adjusting platform, a bowl-shaped light source and a liquid drop moving platen; the second triaxial adjusting platform is installed on a lifting plate of the lifting mechanism. The bowl-shaped light source and the liquid drop moving platen are both arranged on the tail end adjusting plate of the second three-axis adjusting platform. The bowl-shaped light source is positioned directly below the droplet moving platen. The droplet moving platen is made of a non-ferromagnetic transparent material.

The camera assembly comprises a camera, a first support, a second support, an adjusting block, a first adjusting bolt and a second adjusting bolt. The first support is vertically arranged and fixed on the bearing platform; the adjusting block and the first support frame form a sliding pair or a cylindrical pair which slides along the vertical direction, and are locked at different positions through a first adjusting bolt. The second support and the adjusting block form a sliding pair or a cylindrical pair which slides along the horizontal direction, and the sliding pair or the cylindrical pair is locked at different positions through a second adjusting bolt. The camera is installed on the second support, and the head sets up down. The camera can be moved to directly above the droplet moving platen.

Preferably, the bearing platform comprises a top plate, a middle plate, a bottom plate and a section frame. The section bar frame is fixed on the bottom plate. The middle plate is fixed in the middle of the section bar frame. The top plate is fixed on the top of the section bar frame.

Preferably, a plurality of universal wheels are mounted on the bottom surface of the bottom plate.

Preferably, the permanent magnet is an Nd-Fe-B permanent magnet, and the surface magnetic field intensity of the Nd-Fe-B permanent magnet is 1185 Gs.

Preferably, two photoelectric switches are mounted at two ends of one side of the linear module. The photoelectric switch is used for limiting the upper sliding block of the linear module.

Preferably, the magnet placement plate adjusts the platform elevation setting relative to the first triaxial. The droplet moving platen is elevated relative to the second triaxial adjustment stage. The specific height of the elevation is determined according to the magnetic field intensity distribution of the space around the Nd-Fe-B permanent magnet, so that the magnetic field intensity of a magnetic field generated by the Nd-Fe-B permanent magnet at the first triaxial adjusting platform approaches to 0, and the height value of the elevation is set by measuring the magnetic field intensity of different positions around the permanent magnet through a Hall sensor.

Preferably, the lifting mechanism drives the lifting plate at the top to be lifted or lowered through the fork shear mechanism and the guide rail. The lifting mechanism is lifted through manual adjustment or driven by a motor.

Preferably, the top surface of the droplet moving platen is provided with a hydrophobic coating.

Preferably, the magnetic drive liquid drop motion testing device of the invention further comprises a liquid drop feeding assembly. The liquid drop feeding assembly comprises a sample injector clamping mechanism, a sample injector pushing mechanism, a sample injector height adjusting mechanism, an angle adjusting block, a fixing plate and an upright post; the vertical upright post is fixed on the top plate of the bearing platform. The fixed plate is connected to the upright post through the hoop. The staple bolt can slide and rotate on the stand. The injector height adjusting mechanism is arranged on the fixing plate. The sample injector clamping mechanism and the sample pushing and adding mechanism are both arranged on a sliding plate of the sample injector height adjusting mechanism. The sample injector clamping mechanism is positioned below the sample injection pushing mechanism. The injection tube of the injection sample injector is clamped and fixed on the sample injector clamping mechanism. An injection push rod of the injection sample injector is fixed with a sliding plate on the sample pushing and adding mechanism. The height adjusting mechanism of the sample injector and the sample pushing and adding mechanism adopt electric or manual adjustment sliding tables. The injection port of the injection injector is disposed downward. The injection injector can be moved to just above the droplet moving platen.

The testing method of the magnetic driving liquid drop motion testing device comprises the following steps:

step one, mounting the injection injector filled with the magnetic liquid on the regulating liquid drop feeding assembly. The position of the injection injector on the droplet feed assembly is adjusted to be directly above the droplet moving platen. And adjusting the distance from an injection port of the injection sample injector to the liquid drop moving platen by the sample injector height adjusting mechanism, and enabling the injection sample injector to dropwise add a magnetic liquid drop with a preset volume on the liquid drop moving platen by the sample injector pushing mechanism.

Step two, moving away an injection sample injector on the liquid drop feeding assembly; the camera in the camera assembly is adjusted to be directly above the droplet moving platen. The brightness of the bowl-shaped light source is adjusted, so that the edges of the magnetic liquid drops shot by the camera are clear.

Thirdly, adjusting the height of the magnetic liquid drops by a lifting mechanism; and the center position of the magnetic liquid drop is adjusted through the second three-axis adjusting platform, so that the central axis of the magnetic field of the permanent magnet passes through the center position of the magnetic liquid drop.

And step four, adjusting the position of the permanent magnet through a linear module or a first three-axis adjusting platform on the sliding table assembly. And continuously shooting the magnetic liquid drops by the camera in the moving process of the permanent magnet, and recording the behavior process of the magnetic liquid drops. The user can observe the deformation and movement of the magnetic liquid drop in the magnetic field moving process by using the shot picture.

The invention has the following beneficial effects:

1. the invention can adjust the magnetic field by moving the permanent magnet, thereby moving the magnetic liquid drop to move, split and merge; in addition, the permanent magnet can perform one-dimensional long-distance motion and three-dimensional macro motion, and the performance of the magnetic liquid drop can be comprehensively tested.

2. The invention raises the permanent magnet and the magnetic liquid and keeps away from other ferromagnetic materials, thereby ensuring that the magnetic field is more stable in the test and improving the test accuracy.

3. The invention relates to a magnetic driving liquid drop movement operating device which is a device with a compact modular design, and two photoelectric switches additionally arranged on a linear module ensure that a magnetic control platform can move within a parameter range.

Drawings

FIG. 1 is a first overall structural schematic of the present invention;

FIG. 2 is a second overall structural schematic of the present invention;

FIG. 3 is a perspective view of the load-bearing platform of the present invention;

FIG. 4 is a perspective view of the magnetic field displacement assembly of the present invention;

FIG. 6 is a perspective view of a droplet moving assembly according to the present invention;

FIG. 5 is a perspective view of a camera assembly of the present invention;

fig. 7 is a perspective view of a droplet feed assembly according to the present invention.

Detailed Description

The invention will be further explained with reference to the drawings.

As shown in fig. 1 and 2, a magnetic driving liquid drop motion testing device comprises a magnetic field moving assembly I, a camera assembly II, a liquid drop moving assembly III, a liquid drop feeding assembly IV and a bearing platform V; the magnetic field moving assembly I, the camera assembly II, the liquid drop moving assembly III and the liquid drop feeding assembly IV are all arranged on the bearing platform V. The magnetic field moving assembly I and the liquid drop feeding assembly IV are arranged in a straight line.

As shown in fig. 3, the bearing platform v comprises a 60F horsewheel 1, a top plate 2, a middle plate 3, a bottom plate 4 and a profile frame 5. Four corners of the bottom surface of the bottom plate are respectively provided with a 60F Frequus wheel 1. The profile holder 5 is fixed on the base plate 4. The intermediate plate 3 is fixed in the middle of the profile frame 5. The top plate 2 is fixed on top of the profile frame 5.

As shown in fig. 4, the magnetic field moving assembly i comprises a linear module 6, a servo motor 7, an adapter plate 8, a first triaxial adjusting platform 9, a first support bolt 10, a magnet placing plate 11 and a permanent magnet 12; the permanent magnet 12 is an Nd-Fe-B permanent magnet, and the surface magnetic field intensity is 1185 Gs. The effective stroke of the linear module 6 is 150mm and is driven by the servo motor 7. Two photoelectric switches are installed at two ends of one side of the linear module 6. The bottom of the linear module 6 is arranged on the top plate 2 of the bearing platform V through a cylindrical head screw; the first triaxial adjusting platform 9 is arranged on a sliding block of the linear module 6 through the adapter plate 8; a magnet placing plate 11 is installed at an end adjusting plate of the first triaxial adjusting platform 9 at intervals by four first supporting bolts 10. A permanent magnet 12 is fixed to the top surface of the magnet placement plate 11 on the side close to the droplet moving module iii. The magnet placement plate 11 is made of a non-ferromagnetic material. Because the magnet placing plate 11 is elevated by the first supporting bolt 10, the ferromagnetic parts in the linear module 6 and the first triaxial adjusting platform 9 have less influence on the magnetic field generated by the permanent magnet 12, thereby reducing the test error. The magnet placing plate 11 is made of a non-magnetic aluminum plate.

As shown in fig. 5, the droplet moving assembly iii includes a lifting mechanism 21, a second three-axis adjustment platform 22, a bowl-shaped light source 23, a second support bolt 24, and a droplet moving platen 25; the bowl-shaped light source 23 adopts a monochromatic cold light LED lamp with continuously adjustable brightness. The lifting mechanism 21 is arranged on the top plate 2 of the bearing platform V. The lifting mechanism 21 drives the lifting plate at the top of the lifting mechanism 21 to be lifted or lowered through the fork shear mechanism and the guide rail. The lifting mechanism 21 is lifted by manual adjustment or motor drive. A second triaxial adjusting platform 22 is arranged on a lifting plate of the lifting mechanism 21; the droplet moving platen 25 is mounted at intervals on the end regulation plate of the second triaxial regulation stage 22 by four second support bolts 24. Because the liquid drop moving platen 25 is elevated through the second supporting bolt 24, the ferromagnetic parts in the lifting mechanism 21 and the second triaxial adjusting platform 22 have small influence on the measured magnetic liquid drop, thereby reducing the test error. The droplet moving platen 25 is made of transparent glass, and a polytetrafluoroethylene coating is provided on the top surface thereof to produce a smooth hydrophobic surface. The bowl-shaped light source 23 is fixed on the end adjusting plate of the second triaxial adjusting platform 22 by bolts and faces the middle part of the droplet moving platen 25. Bowl form light source 23 can be for II supplementary illumination of camera subassembly, and the setting of being shaded makes the liquid drop edge resolution more clear in the image to let camera subassembly II can shoot the deformation or the removal condition of magnetic drop more clearly.

The first triaxial adjusting platform 9 and the second triaxial adjusting platform 22 can adjust the displacement of the tail end adjusting plate up, down, left, right, front and back. Therefore, the movement condition of the magnetic liquid drops on the liquid drop moving platen 25 when the magnetic field changes is tested, and the detection of the performance of the magnetic liquid drops with different formulas is realized.

As shown in fig. 6, the camera assembly ii includes a camera 13, a first bracket 14, a second bracket 15, an adjustment block 16, a first adjustment bolt 17, a second adjustment bolt 18, a third adjustment bolt 19, a U-shaped mounting bracket, and a camera clamping block 20; the camera 13 employs a high-pixel CCD camera. A first bracket 14 which is vertically arranged is fixed on the top plate 2 of the bearing platform V; the adjusting block 16 and the first bracket 14 form a sliding pair or a cylindrical pair which slides in the vertical direction and is locked at different positions by a first adjusting bolt 17. The second bracket 15 and the adjusting block 16 form a sliding pair or a cylindrical pair which slides in the horizontal direction and is locked at different positions by a second adjusting bolt 18. The U-shaped mounting bracket is fixed to the end of the second bracket 15. Two third adjusting bolts 19 which are coaxially arranged are respectively screwed on the two side plates of the U-shaped mounting rack. The opposite end ends of the two third adjusting bolts 19 are fixed with camera clamping blocks 20. The camera 13 is held between two camera holding blocks 20 with the lens facing downward. By adjusting the relative positional relationship of the first carriage 14, the second carriage 15, and the adjustment block 16, the camera 13 can be adjusted to an appropriate height directly above the droplet moving platen 25. A continuous zoom microscope lens is arranged below the camera 13 according to requirements and used for changing the shooting range by changing the focal length so as to be beneficial to picture composition and clearly observe the behavior of the magnetic liquid drops.

As shown in fig. 7, the droplet feeding assembly iv includes an injector clamping mechanism 26, an advancing injector mechanism 27, an injector height adjusting mechanism 28, an angle adjusting block 29, a fourth adjusting bolt 30, a fixing plate 31, and a column 32; the vertical upright 32 is fixed on the top plate 2 of the bearing platform V. The fixing plate 31 is connected to the upright post 32 through a hoop. The degree of tightness is adjusted through fourth adjusting bolt 30 to the staple bolt. The anchor ear can slide and rotate on the upright 32. The injector height adjusting mechanism 28 is attached to the outer surface of the fixing plate 31. The injector holding mechanism 26 and the pushed-in injector mechanism 27 are both mounted on a slide plate of the injector height adjusting mechanism 28. The injector holding mechanism 26 is located below the advancing sample application mechanism 27. The syringe of the injector is held and fixed on the injector holding mechanism 26. The injection push rod of the injection injector is fixed with the sliding plate on the pushing sample adding mechanism 27. The sample injector height adjusting mechanism 28 and the sample pushing and adding mechanism 27 adopt electric or manual adjustment sliding tables. The injection port of the injection injector is disposed downward. The injector height adjusting mechanism 28 is used to adjust the distance from the injection port of the injection injector to the droplet moving platen 25. The push-loading mechanism 27 is used to push the injection plunger of the injection injector to push the magnetic droplet out onto the droplet moving platen 25.

The testing method of the magnetic driving liquid drop motion testing device comprises the following steps:

step one, the injection injector filled with the magnetic liquid is mounted on the adjustment liquid drop feeding assembly IV. The position of the injection injector on the droplet feed assembly iv is adjusted to be directly above the droplet moving platen 25. The distance from the injection port of the injection injector to the droplet moving platen 25 is adjusted by the injector height adjusting mechanism 28, and the injection injector is caused to drop a predetermined volume of magnetic droplet on the droplet moving platen 25 by pushing the injector mechanism 27. The magnetic liquid drops contain magnetic substances with different volumes, types and concentrations. The magnetic substance comprises a magnetic bead suspension, micron-sized magnetic powder and magnetic steel balls, and the diameter of the magnetic substance is 1 mm.

Step two, moving away an injection sample injector on the liquid drop feeding component IV; the camera 13 in the camera assembly ii is adjusted to be directly above the droplet moving platen 25. The brightness of the bowl-shaped light source 23 is adjusted, so that the edges of the magnetic liquid drops shot by the camera 13 are clearer, and the deformation and the motion state of the liquid drops can be observed conveniently.

Step three, the lifting mechanism 21 adjusts the height of the magnetic liquid drop to a proper position; the center position of the magnetic droplet on the droplet moving platen 25 is adjusted by the second triaxial adjustment stage 22 on the droplet moving assembly iii so that the magnetic field center axis of the permanent magnet 12 on the magnet placement plate 11 passes through the center position of the magnetic droplet.

And step three, adjusting the position of the permanent magnet 12 through the linear module 6 on the sliding table assembly I or the first three-axis adjusting platform 9. The camera 13 continuously shoots the deformation and movement of the magnetic liquid drop in the moving process of the permanent magnet 12, so that the behavior process of the magnetic liquid drop is recorded, and the movement, the splitting and the merging of the liquid drop are observed.